69395-15-9

Basic information

• Product Name: 2-(2-chloro-4-nitro-phenyl)-ethanol
• Synonyms: 2-(2-chloro-4-nitro-phenyl)-ethanol
• CAS NO: 69395-15-9
• Molecular Weight: 201.609
• Mol File: 69395-15-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-(2-chloro-4-nitro-phenyl)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-chloro-4-nitro-phenyl)-ethanol(69395-15-9)
• EPA Substance Registry System: 2-(2-chloro-4-nitro-phenyl)-ethanol(69395-15-9)

Safety Data

• Hazardous Substances Data: 69395-15-9(Hazardous Substances Data)

Usage

Appearance

White to light yellow crystalline solid

Usage

Pharmaceutical intermediate, antimicrobial and antifungal agent in medicinal and personal care products

Role

Building block in organic synthesis for creating complex compounds for pharmaceutical and industrial applications

Hazards

Toxic and hazardous substance, requires proper safety precautions during handling and storage.

Upstream product

• 104-30-3 2-(4-nitrophenyl)ethyl acetate 
• 103-45-7 acetic acid phenethyl ester 
• 350-30-1 3-chloro-4-fluoronitrobenzene 
• 73088-10-5 2-(2-chloro-4-nitro-phenyl)-malonic acid dimethyl ester 
• 50-00-0 formaldehyd 
• 121-86-8 2-chloro-4-nitrotoluene 
• 73088-11-6 2-(2-chloro-4-nitrophenyl)acetic acid 

Downstream Products

• 1026652-81-2 2-chloro-1-(2-methoxymethoxy-ethyl)-4-nitro-benzene 
• 1349744-20-2 [2-(2-chloro-4-nitro-phenyl)-ethyl]-(4-fluoro-benzyl)-carbamic acid tert-butyl ester 
• 1349744-23-5 [2-(4-amino-2-chloro-phenyl)-ethyl]-(4-fluoro-benzyl)-carbamic acid tert-butyl ester 
• 1349744-24-6 (2-{2-chloro-4-[3-(5-cyano-pyrazin-2-yl)-ureido]-phenyl}-ethyl)-(4-fluoro-benzyl)-carbamic acid tert-butyl ester 
• 1349742-95-5 1-{3-chloro-4-[2-(4-fluoro-benzylamino)-ethyl]-phenyl}-3-(5-cyano-pyrazin-2-yl)-urea 
• 858679-83-1 2-chloro-4-nitrophenylacetaldehyde 
• 1349744-18-8 [2-(2-chloro-4-nitro-phenyl)-ethyl]-(4-fluoro-benzyl)-amine 
• 1349744-19-9 N-[2-(2-chloro-4-nitro-phenyl)-ethyl]-(4-fluoro-benzyl)-amine hydrochloride 
• 1437717-28-6 tert-butyl 2-chloro-4-(3-(5-cyanopyrazin-2-yl)ureido)phenethyl(cyclohexylmethyl)carbamate 
• 1437717-20-8 tert-butyl 2-(4-amino-2-chlorophen)ethyl(cyclohexylmethyl)carbamate 
• 1437717-13-9 tert-butyl 2-(2-chloro-4-nitrophenyl)ethyl(cyclohexylmethyl)carbamate 
• 1437717-05-9 2-(2-chloro-4-nitrophenyl)-N-(cyclohexylmethyl)ethanamine 
• 247074-05-1 3-chloro-4-[2-(methoxymethoxy)ethyl]aniline 
• 227467-67-6 1-(2-bromoethyl)-2-chloro-4-nitrobenzene 

Relevant articles and documents

NEODEGRADER CONJUGATES

The present disclosure provides neoDegraders and neoDegraders conjugated to binding moieties. Also provided are compositions comprising the conjugates. The compounds and compositions are useful for treating a disease or condition, e.g., cancer, in a subject in need thereof.

POLYNUCLEOTIDE CONSTRUCTS HAVING BIOREVERSIBLE AND NON-BIOREVERSIBLE GROUPS

The invention features a hybridized polynucleotide construct containing a passenger strand, a guide strand loadable into a RISC complex, and (i) a 3'-terminal or an internucleotide non-bioreversible group in the guide strand; or (ii) a 5'-terminal, a 3'-terminal, or an internucleotide non-bioreversible group in the passenger strand, and a 5'-terminal, a 3'-terminal, or an internucleotide disulfide bioreversible group in the guide strand or the passenger strand. The invention also features methods of delivering a polynucleotide to a cell using the hybridized polynucleotide construct. The invention further features methods of reducing the expression of a polypeptide in a cell using the hybridized polynucleotide construct.

PHARMACEUTICALLY ACTIVE PYRAZINE DERIVATIVES

The invention provides compounds which inhibit or modulate the activity of Chk-1 kinase and which are useful in the treatment of cancer. The compounds have the general formula (1) and salts, N-oxides and tautomers thereof, wherein m is 2, 3 or 4; n is 0 o