69398-48-7Relevant articles and documents
Synthesis, characterization and antifungal activities of some benzenesulphonylamino acid derivatives
Abdel-Ghaffar,Mpango,Ismail,Nanyonga
, p. 389 - 393 (2007/10/03)
Condensation of benzenesulphonyl chloride (1) with a series of amino acids afforded benzenesulphonylamino acids (2a-d). Esterification of the derivatives (2a-d) in methanol gave the corresponding benzensulphonylamino acid methylesters (3a-d), which conden
Palladium-catalysed asymmetric allylic substitution: Synthesis of α- and β-amino acids
Bower, Justin F.,Jumnah, Roshan,Williams, Andrew C.,Williams, Jonathan M. J.
, p. 1411 - 1420 (2007/10/03)
Methodology has been established for the formation of enantiomerically enriched α-amino acids using palladium-catalysed allylic amination. The formation of enantiomerically enriched allylamines has been achieved with high enantioselectivity. Oxidative cleavage of the allylamines provides arylglycine and glutamic acid derivatives. Additionally, enantiomerically enriched β-amino acids have been prepared in high enantiomeric excess. Palladium-catalysed asymmetric allylic substitution is used as the key synthetic transformation.