69414-55-7 Usage
Description
2-[(4-Chloro-2-nitrophenyl)amino]benzoyl Chloride is an organic compound characterized by its unique chemical structure, featuring a chloro-nitrophenyl group attached to a benzoyl chloride moiety. 2-[(4-Chloro-2-nitrophenyl)aMino]benzoyl Chloride is known for its reactivity and serves as a key intermediate in various chemical synthesis processes.
Uses
Used in Pharmaceutical Synthesis:
2-[(4-Chloro-2-nitrophenyl)amino]benzoyl Chloride is used as a reagent for the synthesis of acylpiperazines, which are a class of compounds with potential applications in the pharmaceutical industry. These acylpiperazines may exhibit biological activities that can be harnessed for the development of new drugs.
Used in Clozapine Impurity Synthesis:
In the context of pharmaceutical manufacturing, 2-[(4-Chloro-2-nitrophenyl)amino]benzoyl Chloride serves as an intermediate in the synthesis of a specific impurity associated with Clozapine (C587500). Clozapine is an atypical antipsychotic drug used to treat certain mental/mood disorders. The synthesis of this impurity is crucial for quality control and ensuring the safety and efficacy of Clozapine medications.
Used in Chemical Research:
2-[(4-Chloro-2-nitrophenyl)amino]benzoyl Chloride can also be utilized in chemical research to explore its reactivity and potential applications in the synthesis of other organic compounds. Its unique structure allows for further functionalization and modification, opening up possibilities for the development of new chemical entities with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 69414-55-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,4,1 and 4 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 69414-55:
(7*6)+(6*9)+(5*4)+(4*1)+(3*4)+(2*5)+(1*5)=147
147 % 10 = 7
So 69414-55-7 is a valid CAS Registry Number.
69414-55-7Relevant articles and documents
Direct Reductive Cyclocondensation of the Nitro Group with the Amido Group: Key Role of the Iminophosphorane Intermediate in the Synthesis of 1,4-Dibenzodiazepine Derivatives
Tryniszewski, Micha?,Bujok, Robert,Cmoch, Piotr,Gańczarczyk, Roman,Kulszewicz-Bajer, Irena,Wróbel, Zbigniew
, p. 2277 - 2286 (2019/05/16)
A class of dialkylamino-substituted dibenzodiazepines and their hetero analogues was synthesized by the intramolecular aza-Wittig condensation of the amido group with iminophosphoranes. The one-pot, two-step procedure includes reductive synthesis of the intermediate iminophosphoranes from the corresponding nitroamides and tributylphosphine.
