69538-76-7Relevant articles and documents
Malononitriles & Cyanoesters : Part VI - Synthesis of New Biologically Active Cyanopyridines
Latif, N.,Mishriky, N.,Girgis, N. S.
, p. 147 - 149 (2007/10/02)
3-(2'-Furyl)- and 3-(2'-thienyl)-acrylophenones (I) react with malononitrile in the presence of ammonium acetate to give 2-amino-3-cyano-4,6-disubstituted-pyridines (II).The latter are hydrolysed with alkali to give the corresponding nicotinamides (IV).Th