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6958-33-4

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6958-33-4 Usage

Main Properties

1. Chemical Name: 2-amino-6-(4-nitrophenyl)-4-(2,4,5-trimethoxyphenyl)pyridine-3-carbonitrile
2. Chemical Structure: Complex structure comprising a pyridine ring with various substituents.
3. Functional Groups:
Amino Group (NH2): Attached to position 2 of the pyridine ring.
Nitro Group (NO2): Attached to position 6 of the pyridine ring.
Methoxy Groups (OCH3): Three groups attached to the phenyl ring at positions 2, 4, and 5.
Carbonitrile Group (CN): Attached to position 3 of the pyridine ring, adding to its chemical versatility.
4. Biological Activities/Pharmaceutical Potential: Potential biological activities or pharmaceutical applications due to its structural features.
5. Research Implications: Further research may be warranted to explore its properties and potential uses in various fields.

Amino Group

NH2 group attached at position 2 of the pyridine ring.

Nitro Group

NO2 group attached at position 6 of the pyridine ring.

Methoxy Groups

Three OCH3 groups attached to the phenyl ring at positions 2, 4, and 5.

Carbonitrile Group

CN group attached at position 3 of the pyridine ring.

Chemical Versatility

Presence of the carbonitrile group enhances its potential applications in chemical reactions and synthesis.

Biological/Pharmaceutical Potential

Structural features suggest potential activities or applications in biological and pharmaceutical contexts.

Need for Further Research

Additional investigation is needed to fully understand its properties and potential uses in various fields.

This compound's structural complexity and combination of functional groups make it intriguing for further study in both chemical and biological contexts.

Check Digit Verification of cas no

The CAS Registry Mumber 6958-33-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,9,5 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6958-33:
(6*6)+(5*9)+(4*5)+(3*8)+(2*3)+(1*3)=134
134 % 10 = 4
So 6958-33-4 is a valid CAS Registry Number.

6958-33-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name diethyl 2-acetamido-2-[(5-nitro-1H-indol-3-yl)methyl]propanedioate

1.2 Other means of identification

Product number -
Other names HMS3085P06

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6958-33-4 SDS

6958-33-4Relevant articles and documents

Discovery of IDO1 and DNA dual targeting antitumor agents

Fang, Kun,Wu, Shanchao,Dong, Guoqiang,Wu, Ying,Chen, Shuqiang,Liu, Jianhe,Wang, Wei,Sheng, Chunquan

, p. 9992 - 9995 (2017/12/26)

The development of small molecules for cancer immunotherapy is highly challenging and indoleamine 2,3-dioxygenase 1 (IDO1) represents a promising target. Inspired by the synergistic effects between IDO1 inhibitors and traditional antitumor chemotherapeutics, the first orally active dual IDO1 and DNA targeting agents were designed by the pharmacophore fusion strategy. The bifunctional hybrids exhibited enhanced IDO1 enzyme inhibitory activity and in vitro cytotoxicity as compared to IDO1 inhibitor 1-methyl-tryptophan and DNA alkylating agent melphalan. In a murine LLC tumor model, the dual targeting agents demonstrated excellent antitumor efficacy, highlighting the advantages of this novel design strategy to improve the efficacy of small molecule cancer immunotherapy.

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