69619-23-4

Basic information

• Product Name: Pentanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-oxo-, ethyl ester, (S)-
• CAS NO: 69619-23-4
• Molecular Formula: C12H21NO5
• Mol File: 69619-23-4.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Pentanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-oxo-, ethyl ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pentanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-oxo-, ethyl ester, (S)-(69619-23-4)
• EPA Substance Registry System: Pentanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-oxo-, ethyl ester, (S)-(69619-23-4)

Safety Data

• Hazardous Substances Data: 69619-23-4(Hazardous Substances Data)

Upstream product

• 623-73-4 diazoacetic acid ethyl ester 
• 79069-50-4 Boc-Ala-H 
• 15761-38-3 L-N-Boc-Ala 
• 1071-46-1 hydrogen ethyl malonate 
• 146553-06-2 tert-butyl {(S)-1-[methoxy(methyl)amino]-1-oxopropan-2-yl}carbamate 
• 79069-13-9 (S)-2-t-butoxycarbonylaminopropan-1-ol 
• 54430-64-7 [(1S)-2-imidazol-1-yl-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 35116-15-5 Dibasic magnesium salt of ethyl hydrogen malonate 
• 125814-30-4 BOC-L-alanine-NCA 
• 141-78-6 ethyl acetate 

Downstream Products

• 163659-02-7 (4S,1'S)-1-benzyl-4-(1-tert-butoxycarbonylamino)-2-pyrrolidone 
• 163659-25-4 (4R,1'S)-1-benzyl-4-(1-tert-butoxycarbonylamino)-2-pyrrolidone 
• 163659-01-6 1-benzyl-3-(S)-(1-(S)-tert-butoxycarbonylaminoethyl)pyrrolidine 
• 163659-24-3 1-benzyl-3-(R)-(1-(S)-tert-butoxycarbonylaminoethyl)pyrrolidine 
• 163658-99-9 4-(S)-(1-(S)-aminoethyl)-1-benzyl-2-pyrrolidone 
• 163659-23-2 4-(R)-(1-(S)-aminoethyl)-1-benzyl-2-pyrrolidone 
• 146981-10-4 7-[(R)-3-((S)-1-Amino-ethyl)-pyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid 

Relevant articles and documents

Synthesis of N-protected γ-amino-β-keto-esters from urethane N-carboxyanhydrides (UNCAs)

N-protected γ-amino-β-keto-esters were synthesized from the corresponding N-protected N-carboxyanhydride (UNCAs) by reaction with the lithium enolate of ethyl acetate in good yields. These compounds are precursors of statine derivatives.

HETEROCYCLIC COMPOUNDS AND THEIR USE AS INHIBITORS OF PI3K ACTIVITY

Substituted bicyclic heteroaryls and compositions containing them, for the treatment of general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorde

Tin(ii) chloride assisted synthesis of N-protected γ-amino β-keto esters through semipinacol rearrangement

A facile synthetic route for the preparation of N-protected γ-amino β-keto esters from amino aldehydes and ethyl diazoacetate is described. The two component coupling is facilitated by tin(ii) chloride followed by semipinacol rearrangement leading to the product in quantitative yield. The reaction is mild, instantaneous and compatible with Boc-, Fmoc- and Cbz-amino protecting groups.