69659-80-9

Basic information

• Product Name: TanshinoneIIA
• Synonyms: DS 201;SodiuM tanshinone IIA sulfonate;Sulfotanshinone sodiuM II-A;Tanshinone ⅡASulfonate SodiuM;Sulfotanshinone SodiuM Injection;SodiuM 1,6,6-triMethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate;Phenanthro[1,2-b]furan-2-sulfonicacid, 6,7,8,9,10,11-hexahydro-1,6,6-triMethyl-10,11-dioxo-, sodiuM salt (1:1);Sodium TanshinonⅡA SilateA
• CAS NO: 69659-80-9
• Molecular Formula: C19H17O6S.Na
• Molecular Weight: 396.393
• Product Categories: Natural Plant Extract;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;coronary artery disease;Inhibitors
• Mol File: 69659-80-9.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: TanshinoneIIA(CAS DataBase Reference)
• NIST Chemistry Reference: TanshinoneIIA(69659-80-9)
• EPA Substance Registry System: TanshinoneIIA(69659-80-9)

Safety Data

• Hazardous Substances Data: 69659-80-9(Hazardous Substances Data)

Usage

Description

TanshinoneIIA is a naturally occurring compound derived from the roots of the Salvia miltiorrhiza plant, commonly known as Danshen or Red Sage. It is a lipophilic component with a unique chemical structure, characterized by its red color and antioxidant properties. TanshinoneIIA has been extensively studied for its potential therapeutic effects and is recognized for its ability to improve blood circulation, reduce inflammation, and exhibit anti-cancer properties.

Uses

Used in Pharmaceutical Industry:
TanshinoneIIA is used as a therapeutic agent for its various pharmacological effects, including anti-inflammatory, antioxidant, and anti-cancer activities. It has been found to be particularly effective in treating conditions such as hemorrhagic shock, asthma, and cardiovascular diseases.
Used in Anticancer Applications:
TanshinoneIIA is employed as an anticancer agent, targeting various types of cancer cells and exhibiting inhibitory effects on tumor growth and progression. It modulates multiple signaling pathways involved in cancer development and has shown potential in enhancing the efficacy of conventional chemotherapeutic drugs, making it a promising candidate for cancer treatment.
Used in Cardiovascular Applications:
TanshinoneIIA is used as a cardiovascular agent to improve blood circulation and reduce inflammation. It has been shown to have beneficial effects on conditions such as hemorrhagic shock, where it can help ameliorate organ failure or dysfunction caused by the shock.
Used in Respiratory Applications:
In the treatment of asthma, TanshinoneIIA is used as a therapeutic agent to alleviate symptoms and improve lung function. Its anti-inflammatory and antioxidant properties contribute to its effectiveness in managing this respiratory condition.

InChI:InChI=1/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1