69704-27-4

Basic information

• Product Name: 1,4-dipropoxybut-2-yne
• Synonyms: 1,4-dipropoxybut-2-yne;1,4-Dipropoxy-2-butyne
• CAS NO: 69704-27-4
• Molecular Formula: C₁₀H₁₈O₂
• Molecular Weight: 170.24872
• EINECS: 274-089-1
• Mol File: 69704-27-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 232.3°C at 760 mmHg
• Flash Point: 76.9°C
• Appearance: /
• Density: 0.897g/cm³
• Vapor Pressure: 0.0902mmHg at 25°C
• Refractive Index: 1.438
• CAS DataBase Reference: 1,4-dipropoxybut-2-yne(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-dipropoxybut-2-yne(69704-27-4)
• EPA Substance Registry System: 1,4-dipropoxybut-2-yne(69704-27-4)

Safety Data

• Hazardous Substances Data: 69704-27-4(Hazardous Substances Data)

Usage

General Description

1,4-dipropoxybut-2-yne is a chemical compound with the molecular formula C10H16O2. It is a derivative of but-2-yne, containing two propoxy (C3H7O) groups attached to the 1 and 4 positions of the carbon chain. 1,4-dipropoxybut-2-yne is a colorless liquid at room temperature and is used as a chemical intermediate in organic synthesis. It is mainly used in the production of pharmaceuticals, agrochemicals, and other specialty chemicals. 1,4-dipropoxybut-2-yne is also employed as a reagent in research laboratories for the preparation of various organic compounds. However, its use should be handled with caution due to its potential flammability and irritant properties.

InChI:InChI=1/C10H18O2/c1-3-7-11-9-5-6-10-12-8-4-2/h3-4,7-10H2,1-2H3

Upstream product

• 4301-15-9 ethynyldimagnesium dibromide 
• 505-84-0 dipropoxymethane 
• 3587-57-3 chloromethyl propyl ether 
• 14630-40-1 Bis(trimethylsilyl)ethyne 
• 110-65-6 1,4-dihydroxybut-2-yne 
• 106-94-5 propyl bromide 

Relevant articles and documents

An Easy Preparation of α-Allenic Ethers and Tertiary α-Allenic Amines

α-Allenic ethers 2 are prepared by the reaction of 1,4-dialkoxy-2-butynes 1 with lithium aluminium hydride and magnesium bromide.Tertiary α-allenic amines 4 are obtained by treating 4-dialkylamino-1-methoxy-2-butynes 3 with lithium aluminium hydride and aluminium chloride.

Transannular [4 + 2] Cycloaddition Reactions of Cobalt-Complexed Macrocyclic Dienynes

The first transannular [4 + 2] cycloaddition reactions of macrocyclic dicobalt hexacarbonyl-dienyne complexes were demonstrated. Complexes were conveniently prepared through palladium(II)-catalyzed intramolecular oxidative cyclization of bis(vinylboronate esters) followed by complexation with dicobalt octacarbonyl. Transannular [4 + 2] cycloaddition reactions of the complexes occurred at lower temperatures and shorter times than transannular Diels-Alder reactions of metal-free dienynes. Intermolecular control reactions confirmed the effect of cobalt complexation on [4 + 2] cycloaddition reactions of unactivated alkynes and dienes.