69706-72-5

Basic information

• Product Name: (Z)-3-Benzylamino-6-hydroxy-1-phenyl-hex-2-en-1-one
• CAS NO: 69706-72-5
• Molecular Weight: 295.381
• Mol File: 69706-72-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (Z)-3-Benzylamino-6-hydroxy-1-phenyl-hex-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-3-Benzylamino-6-hydroxy-1-phenyl-hex-2-en-1-one(69706-72-5)
• EPA Substance Registry System: (Z)-3-Benzylamino-6-hydroxy-1-phenyl-hex-2-en-1-one(69706-72-5)

Safety Data

• Hazardous Substances Data: 69706-72-5(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 304678-93-1 1-phenyl-6-bromo-1,3-hexanedione 
• 304678-98-6 2-[Dihydro-furan-(2Z)-ylidene]-1-phenyl-ethanone 
• 69706-65-6 (E)-α-(Tetrahydro-2-furylidene)acetophenone 

Relevant articles and documents

Syntheses and biological evaluation of 3-substituted amino-1-aryl-6-hydroxy-hex-2-ene-1-ones as antioxidant and hypolipidemic agents

A new series of compounds belonging to 3-substituted amino-1-aryl-6-hydroxy-hex-2-ene-1-ones (4-12a-e) have been synthesized and evaluated for antioxidant and hypolipidemic activities. Amongst all the synthesized compounds, seven compounds, namely 5b, 5d, 6e, 8a, 8b, 10b and 11a, exhibit better antioxidant activity than probucol. Two compounds, 5d and 10b, have been evaluated in detail for antioxidant and hypolipidemic activities and show comparable activity profile to that of probucol and guggulipid. From the present study it may be postulated that the mechanism of action of these compounds could be through activation of lecithin cholesterol acyltransferase (LCAT), liver lipolytic activity, increased faecal bile acid secretion and inhibition of hepatic cholesterol biosynthesis. Copyright (C) 2000 Elsevier Science Ltd.