697301-71-6

Basic information

• Product Name: (1-phenylvinyl)carbamic acid benzyl ester
• Synonyms: (1-phenylvinyl)carbamic acid benzyl ester
• CAS NO: 697301-71-6
• Molecular Weight: 253.301
• Mol File: 697301-71-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (1-phenylvinyl)carbamic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1-phenylvinyl)carbamic acid benzyl ester(697301-71-6)
• EPA Substance Registry System: (1-phenylvinyl)carbamic acid benzyl ester(697301-71-6)

Safety Data

• Hazardous Substances Data: 697301-71-6(Hazardous Substances Data)

Upstream product

• 31139-36-3 dibenzyl dicarbonate 
• 98-86-2 acetophenone 
• 75-16-1 methylmagnesium bromide 
• 100-47-0 benzonitrile 
• 501-53-1 benzyl chloroformate 
• 909906-72-5 (E)-benzyl 1-phenylethylidenecarbamate 

Downstream Products

• 152140-55-1 (R)-(-)-1,3-diphenylpent-4-ene-1-one 
• 1360873-04-6 C₂₄H₁₈N₂O₂ 
• 1360873-30-8 C₂₄H₁₆F₂N₂O₂ 

Relevant articles and documents

Direct Enamido C(sp2)?H Diphosphorylation Enabled by a PCET-Triggered Double Radical Relay: Access to gem-Bisphosphonates

Herein we report a novel and straightforward protocol for the construction of valuable gem-BPs by means of proton-coupled electron-transfer (PCET)-triggered enamido C(sp2)?H diphosphorylation. This reaction represents a rare example of realizing the challenging double C?P bond formation at a single carbon atom, thus providing facile access to a broad variety of structurally diverse bisphosphonates from simple enamides under silver-mediated conditions. Initial mechanistic studies demonstrated that the diphosphorylation involves two rounds of PCET-initiated radical relay process.

Synthesis of 2,3-Dihydro-1H-azepine and 1H-Azepin-2(3H)-one Derivatives from Intramolecular Condensation between Stable Tertiary Enamides and Aldehydes

A new strategy to construct 2,3-dihydro-1H-azepine and 1H-azepin-2(3H)-one heterocyclic rings is reported based on emerging tertiary enamide synthons. Under very mild conditions employing BBr3 as a Lewis acid catalyst and P2O5 as an additive, tertiary enamides that contain a formyl group underwent highly efficient and scalable intramolecular cyclic condensation to afford diverse 2,3-dihydro-1H-azepine and 1H-azepin-2(3H)-one derivatives in 71-96% yields. The reaction proceeded most probably through a nucleophilic addition of enamides to aldehyde, deprotonation, and dehydration cascade. Application of the method in the synthesis of dihydro-azepino[2,1-a]isoindol-5-ones, the core structure of naturally occurring lennoxamine, was also demonstrated.

A mild and convenient synthesis of N-carbobenzyloxy ketimines

N-Carbobenzyloxy (Cbz) ketimines were prepared conveniently from N-Cbz amines by oxidation with N-tert-butylbenzenesulfinimidoyl chloride. The Royal Society of Chemistry 2006.