69750-00-1

Basic information

• Product Name: 2-chloro-6-phenyl-nicotinamide
• Synonyms: 2-chloro-6-phenyl-nicotinamide
• CAS NO: 69750-00-1
• Molecular Weight: 232.669
• Mol File: 69750-00-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-6-phenyl-nicotinamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-6-phenyl-nicotinamide(69750-00-1)
• EPA Substance Registry System: 2-chloro-6-phenyl-nicotinamide(69750-00-1)

Safety Data

• Hazardous Substances Data: 69750-00-1(Hazardous Substances Data)

Upstream product

• 69750-01-2 2-chloro-6-phenylpyridine-3-carboxylic acid 
• 38496-18-3 2,6-dichloropyridine-3-carboxylic acid 
• 98-80-6 phenylboronic acid 

Downstream Products

• 43083-14-3 2-chloro-3-cyano-6-phenylpyridine 

Relevant articles and documents

PYRIDO [3',2' :4,5] THIENO [3, 2-D] PYRIMIDIN- 4 - YLAMINE DERIVATIVES AND THEIR THERAPEUTICAL USE

The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain fused triaryl amine compounds of the following formula (for convenience, collectively referred to herein as "FTA compounds"), which, inter alia, inhibit LIM kinase (LIMK) activity. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit LIMK activity, and in the treatment of diseases and conditions that are mediated by LIMK, that are ameliorated by the inhibition of LIMK activity, etc., including proliferative conditions such as cancer (e.g., breast cancer, prostate cancer, melanoma, glioma, etc.), as well as vasodilation (including, e.g., hypertension, angina, cerebral vasospasm, and ischemia following subarachnoid hemorrhage), neurodegenerative disorders, atherosclerosis, fibrosis, and inflammatory diseases (including, e.g., Crohn's disease and chronic obstructive pulmonary disease (COPD)), and glaucoma (also known as ocular hypertension).