69751-74-2 Usage
General Description
2-Amino-3,5-dibromobenzophenone is a chemical compound with the molecular formula C13H8Br2NO. It is a derivative of benzophenone containing two bromine atoms on the 3 and 5 positions of the phenyl ring. 2-AMINO-3,5-DIBROMOBENZOPHENONE is primarily used as a starting material in the synthesis of pharmaceuticals, dyes, and other organic compounds. It is also used as a photoinitiator in the production of plastics and adhesives. Additionally, 2-amino-3,5-dibromobenzophenone possesses potential biological activity and is being studied for its potential role in the development of new drugs and treatments. However, it is important to handle this chemical with care, as it may have hazardous properties and should be used in a controlled laboratory setting.
Check Digit Verification of cas no
The CAS Registry Mumber 69751-74-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,7,5 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 69751-74:
(7*6)+(6*9)+(5*7)+(4*5)+(3*1)+(2*7)+(1*4)=172
172 % 10 = 2
So 69751-74-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H9Br2NO/c14-9-6-10(12(16)11(15)7-9)13(17)8-4-2-1-3-5-8/h1-7H,16H2
69751-74-2Relevant articles and documents
Structure-Activity Relationship Studies of Retro-1 Analogues against Shiga Toxin
Abdelkafi, Hajer,Michau, Aurélien,Pons, Valérie,Ngadjeua, Flora,Clerget, Alexandra,Ait Ouarab, Lilia,Buisson, David-Alexandre,Montoir, David,Caramelle, Lucie,Gillet, Daniel,Barbier, Julien,Cintrat, Jean-Christophe
, p. 8114 - 8133 (2020/09/21)
High-throughput screening has shown that Retro-1 inhibits ricin and Shiga toxins by diminishing their intracellular trafficking via the retrograde route, from early endosomes to the Golgi apparatus. To improve the activity of Retro-1, a structure-activity relationship (SAR) study was undertaken and yielded an analogue with a roughly 70-fold better half-maximal effective concentration (EC50) against Shiga toxin cytotoxicity measured in a cell protein synthesis assay.