69808-76-0

Basic information

• Product Name: N-benzyl-1H-indole-2-carboxamide
• Synonyms: N-benzyl-1H-indole-2-carboxamide
• CAS NO: 69808-76-0
• Molecular Weight: 250.3
• Mol File: 69808-76-0.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: N-benzyl-1H-indole-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-1H-indole-2-carboxamide(69808-76-0)
• EPA Substance Registry System: N-benzyl-1H-indole-2-carboxamide(69808-76-0)

Safety Data

• Hazardous Substances Data: 69808-76-0(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 586959-21-9 1H-1,2,3-benzotriazol-1-yl(1H-indol-2-yl)methanone 
• 69808-63-5 1-(indole-2-carbonyl)-1H-imidazole 
• 1477-50-5 Indole-2-carboxylic acid 
• 58881-45-1 Indole-2-carbonyl chloride 

Downstream Products

• 1316845-39-2 2-benzyl-3-(4-methylphenyl)-4-iodo-5-(4-chlorophenyl)-5,10-dihydroazepino[3,4-b]indol-1(2H)-one 
• 1316845-41-6 2-benzyl-3-cyclohex-1-enyl-4-iodo-5-(4-ethoxyphenyl)-5,10-dihydroazepino[3,4-b]indol-1(2H)-one 
• 1316845-37-0 2-benzyl-3-(4-methylphenyl)-4-iodo-5-(4-ethoxyphenyl)-5,10-dihydroazepino[3,4-b]indol-1(2H)-one 
• 1316845-35-8 2-benzyl-3-phenyl-4-iodo-5-(3,4-dimethoxyphenyl)-5,10-dihydroazepino[3,4-b]indol-1(2H)-one 
• 149685-64-3 N-((1H-indol-2-yl)methyl)-1-phenylmethanamine 

Relevant articles and documents

Cu(OAc)2-Triggered Cascade Reaction of Malonate-Tethered Acyl Oximes with Indoles, Indole-2-alcohols, and Indole-2-carboxamides

A Cu(OAc)2-promoted cascade reaction of malonate-tetherd acyl oximes with indoles, indole-2-alcohols, or indole-2-carboxmides provides facile access to polysubstituted 3-pyrrolin-2-ones. The reaction features the generation of two adjacent elec

AMIDATION METHOD AND ESTERIFICATION METHOD USING SULFONIC ACID HALIDE

PROBLEM TO BE SOLVED: To provide a safe and economical method for rapidly synthesizing amides and esters in high yield. SOLUTION: There is provided a method for amidating an amine or a derivative thereof using a sulfonic acid halide, where a sulfonic acid halide is allowed to act as an activator on a carboxylic acid or a derivative thereof to synthesize an active ester, and the active ester is reacted with an amine or a derivative thereof as a nucleophile to amidate the amine or the derivative thereof to obtain a corresponding amide or a derivative thereof. In a similar manner, a sulfonic acid halide is allowed to act as an activator on a carboxylic acid or a derivative thereof to synthesize an active ester, and the active ester is reacted with an alcohol or a derivative thereof as a nucleophile to esterify the alcohol or the derivative thereof to obtain a corresponding ester or a derivative thereof. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2016,JPO&INPIT

Synthesis of heteroarylogous 1H-indole-3-carboxamidines via a three-component interrupted Ugi reaction

A novel one-pot multicomponent synthesis of heteroarylogous 1H-indole-3-carboxamidines starting from readily available N-alkyl-N-(1H-indol-2-ylmethyl)amines, isocyanides, and carbonyl compounds is reported. The strategy exploits the ability of the indole nucleus to interrupt the classical Ugi reaction, by intercepting the nascent nitrilium ion.