698357-75-4Relevant articles and documents
Syntheses and characterization of the acyl glucuronide and hydroxy metabolites of diclofenac
Kenny, Jane R.,Maggs, James L.,Meng, Xiaoli,Sinnott, Deborah,Clarke, Stephen E.,Park, B. Kevin,Stachulski, Andrew V.
, p. 2816 - 2825 (2007/10/03)
In humans, metabolism of the commonly used nonsteroidal antiinflammatory drug diclofenac 1 yields principally the 4′-hydroxy 2, 5-hydroxy 3, and acyl glucuronide 4 metabolites. All three metabolites have been implicated in rare idiosyncratic adverse react