69838-98-8

Basic information

• Product Name: 1-(4-Methoxybenzoyl)pyrrolidine, 97%
• Synonyms: 1-(4-Methoxybenzoyl)pyrrolidine, 97%;methyl 4-(1-pyrrolidinylcarbonyl)phenyl ether
• CAS NO: 69838-98-8
• Molecular Formula: C₁₂H₁₅NO₂
• Molecular Weight: 205.253
• Mol File: 69838-98-8.mol
• Article Data: 57

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4-Methoxybenzoyl)pyrrolidine, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Methoxybenzoyl)pyrrolidine, 97%(69838-98-8)
• EPA Substance Registry System: 1-(4-Methoxybenzoyl)pyrrolidine, 97%(69838-98-8)

Safety Data

• Hazardous Substances Data: 69838-98-8(Hazardous Substances Data)

Usage

Purity

97%

Chemical Structure

A pyrrolidine derivative with a 4-methoxybenzoyl moiety attached to the nitrogen atom.

Usage

Commonly used in organic synthesis and research as a building block for the synthesis of various organic molecules.

Applications

a. Production of pharmaceuticals
b. Production of agrochemicals
c. Production of other fine chemicals

Potential Applications

Development of novel materials and catalysts.

Importance

Valuable reagent for researchers and chemists in various scientific fields due to its chemical structure and high purity.

Upstream product

• 696-62-8 para-iodoanisole 
• 116858-81-2 trimethylpyrrolidinylcarbonylstannane 
• 116883-46-6 tributylpyrrolidinylcarbonylstannane 
• 116858-84-5 triphenylpyrrolidinylcarbonylstannane 
• 121767-18-8 C₁₀H₁₆N₂O₂Se₂ 
• 100-66-3 methoxybenzene 
• 123-75-1 pyrrolidine 
• 100-07-2 4-methoxy-benzoyl chloride 
• 201230-82-2 carbon monoxide 
• 693-02-7 hex-1-yne 
• 123-11-5 4-methoxy-benzaldehyde 
• 100-09-4 4-methoxybenzoic acid 
• 13939-06-5 molybdenum hexacarbonyl 
• 15226-74-1 dicobalt octacarbonyl 

Downstream Products

• 72432-10-1 aniracetam 
• 478929-28-1 (4-hydroxyphenyl)(pyrrolidin-1-yl)methanone 
• 80282-57-1 (4-methoxyphenyl)(pyrrolidin-1-yl)methanethione 
• 1110635-88-5 toluene-4-sulfonic acid 5-[5-methoxy-2-(pyrrolidine-1-carbonyl)phenyl]-5-phenylpent-4-enyl ester 
• 1110635-92-1 (2-(1-butylidenehex-2-ynyl)-4-methoxyphenyl)pyrrolidin-1-ylmethanone 
• 1110635-86-3 (4-methoxy-2-(1-phenylhex-1-enyl)phenyl)pyrrolidin-1-ylmethanone 
• 1110635-90-9 (2-(5-bromo-1-phenylpent-1-enyl)-4-methoxyphenyl)pyrrolidin-1-ylmethanone 
• 1110635-84-1 (2-(1,2-diphenylvinyl)-4-methoxyphenyl)pyrrolidin-1-ylmethanone 
• 1187051-95-1 (4-methoxy-2-(3-methylbut-2-enyl)phenyl)(pyrrolidin-1-yl)methanone 
• 1373312-51-6 C₂₆H₂₈N₂O₄S 
• 1612778-15-0 C₂₃H₂₁F₉N₂O₃S 
• 92498-02-7 5-methoxy-2-phenylisoindoline-1,3-dione 

Relevant articles and documents

Photocatalytic aldehydes/alcohols/toluenes oxidative amidation over bifunctional Pd/MOFs: Effect of Fe-O clusters and Lewis acid sites

Heterogeneous photocatalytic organic synthesis is fascinating because of the utilization of ubiquitous solar light for chemical transformations. Here, three Fe-MOFs with different Fe-O clusters, Lewis acid sites and morphologies were synthesized through coordination structure engineering. Pd/Fe-MOFs nanocomposites were used to challenge the amide bond green synthesis with visible light. Pd/MIL-101(Fe) exhibited the best photocatalytic performance due to the easily excited Fe3-μ3-oxo clusters for light absorption, the efficient photogenerated carriers separation and migration, the large amount of Lewis acid sites based aldehydes and amines condensation promotion and the efficient O2 reduction to superoxide radicals over photogenerated electron-rich Pd NPs. Various aldehydes, alcohols and toluenes could be transformed to amide compounds with amines over Pd/MIL-101(Fe) with just oxygen or air as the green oxidant and water as the by-product. One-pot C–C cross-coupling and photo-redox C–N coupling cascade reactions could also be achieved over Pd/MIL-101(Fe). This work shed light on the efficient and sustainable amide bonds synthesis.

Amide Bond Formation via Aerobic Photooxidative Coupling of Aldehydes with Amines Catalyzed by a Riboflavin Derivative

We report an effective, operationally simple, and environmentally friendly system for the synthesis of tertiary amides by the oxidative coupling of aromatic or aliphatic aldehydes with amines mediated by riboflavin tetraacetate (RFTA), an inexpensive organic photocatalyst, and visible light using oxygen as the sole oxidant. The method is based on the oxidative power of an excited flavin catalyst and the relatively low oxidation potential of the hemiaminal formed by amine to aldehyde addition.

Cobalt(iii)-catalyzed C-H amidation of: N, N -dialkyl thiobenzamides by sulfur coordination

An efficient inexpensive cobalt(iii)-catalyzed intermolecular amidation of N,N-dialkyl thiobenzamides with 1,4,2-dioxazol-5-ones via C-H bond activation is described. The reaction proceeds with high functional group tolerance under external oxidant free conditions, providing a straightforward approach for the direct modification of thioamide derivatives, which are prevalent organic motifs found in vital biological and pharmaceutical molecules. This journal is