69917-80-2

Basic information

• Product Name: METHYL 3-(2-PYRROLYL)PROPANOATE
• Synonyms: METHYL 3-(2-PYRROLYL)PROPANOATE;METHYL 3-(1H-PYRROL-2-YL)PROPANOATE;1H-Pyrrole-2-propanoic Acid Methyl Ester;2-(2-Methoxycarbonylethyl)pyrrole;Methyl-3-(2-pyrrolyl)propionate;Methyl 3-(2-pyrrolyl)propionate [ 2-(2-Methoxycarbonylethyl)pyrrole];3-(1H-pyrrol-2-yl)-propionic acid methyl ester
• CAS NO: 69917-80-2
• Molecular Formula: C₈H₁₁NO₂
• Molecular Weight: 153.17844
• Product Categories: Aromatics Compounds;Aromatics
• Mol File: 69917-80-2.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 75°C/0/3mmHg.
• Flash Point: 105℃
• Appearance: Clear to light yellow liquid
• Density: 1.117
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Sparingly)
• PKA: 17.34±0.50(Predicted)
• CAS DataBase Reference: METHYL 3-(2-PYRROLYL)PROPANOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-(2-PYRROLYL)PROPANOATE(69917-80-2)
• EPA Substance Registry System: METHYL 3-(2-PYRROLYL)PROPANOATE(69917-80-2)

Safety Data

• Hazardous Substances Data: 69917-80-2(Hazardous Substances Data)

Usage

Chemical Properties

Clear to Light Yellow Liquid

Uses

Methyl 3-(2-Pyrrolyl)propanoate (cas# 69917-80-2) is a compound useful in organic synthesis.

Upstream product

• 186581-53-3 diazomethane 
• 408309-29-5 3-(1H-pyrrol-2-yl)propanoic acid 
• 49616-56-0 3-(pyrrol-2-yl)acrylic acid methyl ester 
• 91642-12-5 Diethyl 2-<(pyrrol-2-yl)methylidene>malonate 
• 100371-16-2 pyrrol-2-ylmethyl-malonic acid diethyl ester 
• 1017802-42-4 methyl (E)-3-(6'-ethoxy-5',6'-dihydro-4'H-1',2'-oxazin-3'-yl)propenoate 
• 1190426-25-5 methyl (E)-3-[N-(2-pyridylsulfonyl)pyrrol-2-yl]acrylate 
• 32585-91-4 3-(1H-Pyrrol-2-yl)-acrylic acid methyl ester 
• 1003-29-8 2-pyrrole aldehyde 

Downstream Products

• 10087-64-6 2,2'-bipyrrole 
• 1313876-81-1 C₂₇H₃₂BF₂N₃O₄ 
• 1451009-80-5 5,5-difluoro-1,3-dimethyl-7-(3-(4-phenethyl-1H-1,2,3-triazol-1-yl)propyl)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide 
• 1451009-89-4 5,5-difluoro-1,3-dimethyl-7-(3-(5-phenethyl-1H-1,2,3-triazol-1-yl)propyl)-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide 
• 1451009-84-9 7-(3-benzamidopropyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide 
• 1451009-87-2 7-(3-(cyclohexanecarboxamido)propyl)-5,5-difluoro-1,3-dimethyl-5H-dipyrrolo[1,2-c:1',2'-f][1,3,2]diazaborinin-4-ium-5-uide 

Relevant articles and documents

Synthesis of cystamidin A (pyrrole-3-propanamide), a reported calpain inhibitor

The reported calpain inhibitor cystamidin A (1a, pyrrole-3-propanamide) and a regioisomer, pyrrole-2-propanamide (1b) have been synthesized from the corresponding pyrrolecarboxaldehydes. The previously assigned structure of cystamidin A is confirmed. However, neither synthetic cystamidin A nor regioisomer 1b inhibits recombinant human calpain I.

FLUORESCENT ENDOPLASMIC RETICULUM TRACKERS FOR LIVE CELL IMAGING OF PATHOGENIC YEAST

Particular 1,2,3-triazole- and 1,2,4-triazole-based compounds can be used as fluorescent probes. The compounds can optionally be substituted with one or two fluorine atoms. The compounds are effective as specific endoplasmatic reticulum (ER)-trackers for live cell imaging in a fungal cell, such as a pathogenic yeast. Compositions including the fluorescent probes can be used in methods for tracking the endoplasmic reticulum in a fungal cell.

KETONE INHIBITORS OF LYSINE GINGIPAIN

The present invention provides compounds according to Formula (I) as described herein, and their use for inhibiting the lysine gingipain protease (Kgp) from the bacterium Porphyromonas gingivalis. Also described are gingipain activity probe compounds and methods for assaying gingipain activity are also described, as well as methods for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease.