700-91-4

Basic information

• Product Name: 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE
• Synonyms: 2-Phenyl-1-pyrroline
• CAS NO: 700-91-4
• Molecular Formula: C₁₀H₁₁N
• Molecular Weight: 145.2
• Product Categories: pharmacetical
• Mol File: 700-91-4.mol
• Article Data: 62

Chemical Properties

• Melting Point: 44-45 °C
• Boiling Point: 244.7°C at 760 mmHg
• Flash Point: 101.8°C
• Appearance: /
• Density: 1.12g/cm³
• Vapor Pressure: 0.0468mmHg at 25°C
• Refractive Index: 1.611
• PKA: 7.30±0.20(Predicted)
• CAS DataBase Reference: 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE(700-91-4)
• EPA Substance Registry System: 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE(700-91-4)

Safety Data

• Hazardous Substances Data: 700-91-4(Hazardous Substances Data)

Usage

General Description

5-Phenyl-3,4-dihydro-2H-pyrrole is a chemical compound with the molecular formula C10H11N. It is a heterocyclic compound containing a pyrrole ring with a phenyl group attached. 5-PHENYL-3,4-DIHYDRO-2H-PYRROLE is a colorless liquid at room temperature and is commonly used in the synthesis of various pharmaceuticals and agrochemicals. It has also been studied for its potential pharmacological activities, including its role as a dopamine receptor antagonist. Additionally, 5-phenyl-3,4-dihydro-2H-pyrrole has been investigated for its potential use in the development of new materials and functional molecules due to its unique structure and reactivity. Overall, this compound has versatile applications in the field of organic chemistry and drug development.

InChI:InChI=1/C9H10N2/c1-2-9(11-5-1)8-3-6-10-7-4-8/h3-4,6-7H,1-2,5H2

Upstream product

• 5343-98-6 4-oxo-4-phenylbutanenitrile 
• 5264-35-7 2-methoxy-1-pyrroline 
• 591-51-5 phenyllithium 
• 14468-90-7 N-trimethylsilyl-pyrrolidin-2-one 
• 108-86-1 bromobenzene 
• 99075-08-8 1-Hydroxy-2-phenylpyrrolidine 
• 73434-11-4 2-Hydroxy-2-phenylpyrrolidine 
• 116437-41-3 tert-butyl (4-oxo-4-phenyl-butyl)-carbamate 
• 135469-70-4 4-phenyl-3-butyn-1-amine 
• 92014-43-2 1-(2'-methylbenzyl)-2-phenyl-1-pyrrolinium perchlorate 
• 92014-45-4 1-(2'-((trimethylsilyl)methyl)benzyl)-2-phenyl-1-pyrrolinium perchlorate 
• 125330-80-5 3-benzoyl-N-vinylpyrrolidin-2-one 
• 100-47-0 benzonitrile 
• 95091-93-3 1-(3-bromopropyl)-2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentane 

Downstream Products

• 24517-60-0 N-(4-oxo-4-phenylbutyl)acetamide 
• 1006-64-0 2-(phenyl)pyrrolidine 
• 83314-43-6 1-methyl-5-phenyl-3,4-dihydro-2H-pyrrolium; iodide 
• 69105-64-2 4-methyl-6-phenyl-1-azabicyclo<4.3.0>non-3-en-2-one 
• 69275-27-0 endo-3-methoxy-4,4-dimethyl-5-phenyl-1-azabicyclo<3.3.0>octan-2-one 
• 69275-27-0 exo-3-methoxy-4,4-dimethyl-5-phenyl-1-azabicyclo<3.3.0>non-3-en-2-one 
• 911796-43-5 2-phenyl-2-(1-methoxy-2-cyclopropylprop-2-yl)pyrrolidine 
• 76778-94-4 5-phenyl-1-aza-3-oxabicyclo<3.3.0>octane 
• 89730-99-4 3-Dicyanomethyl-2-phenyl-pyrrol 
• 89730-97-2 3-Tricyanovinyl-2-phenyl-Δ2-pyrrolin 
• 78744-86-2 2-Phenyl-3-(2'-hydroxybenzyl)-Δ1-pyrrolin 
• 89731-02-2 3-(Cyano-carbethoxy-methyl)-2-phenyl-pyrrol 
• 98055-36-8 1,3,7a-Triphenyl-5,6,7,7a-tetrahydro-pyrrolo<2,1-b>-1,2,4-triazol 
• 69105-67-5 5-phenyl-6-vinyl-1-azabicyclo<3.2.0>heptane 

Relevant articles and documents

Novel Kumada coupling reaction to access cyclic (2-azaallyl)stannanes. Cycloadditions of cyclic nonstabilized 2-azaallyllithium species derived from cyclic (2-azaallyl)stannanes

A Kumada cross-coupling reaction involving organomagnesium reagents and (3-methylthio-2-azaallyl)stannanes with a Ni(O) catalyst provided cyclic nonstabilized (2-azaallyl)stannanes in moderate to good yields. Primary alkyl, aryl, and allylic organomagnesi

Domino Synthesis of 4-Alkylidene-3,4-dihydro-2H-pyrroles from Homopropargyl Sulfonamides and Aldehydes

Abstract: We describe a domino synthesis of 4-alkylidene-3,4-dihydro-2H-pyrroles from aryl-substituted homopropargyl sulfonamides and aldehydes promoted by cheap and easy-to-handle TsOH ? H2O. The present reactions proceed through cyclocondensation of α-sulfonamidoethyl-α,β-enone intermediates, which are formed by ring-cleavage of 3-acylpyrrolidines corresponding to aza-Prins cyclized intermediates. By controlling the conditions, 3-acylpyrrolidines can be obtained.

Iron(II)-Catalyzed Aerobic Biomimetic Oxidation of Amines using a Hybrid Hydroquinone/Cobalt Catalyst as Electron Transfer Mediator

Herein we report the first FeII-catalyzed aerobic biomimetic oxidation of amines. This oxidation reaction involves several electron transfer steps and is inspired by biological oxidation in the respiratory chain. The electron transfer from the amine to molecular oxygen is aided by two coupled catalytic redox systems, which lower the energy barrier and improve the selectivity of the oxidation reaction. An iron hydrogen transfer complex was utilized as the substrate-selective dehydrogenation catalyst along with a bifunctional hydroquinone/cobalt Schiff base complex as a hybrid electron transfer mediator. Various primary and secondary amines were oxidized in air to their corresponding aldimines or ketimines in good to excellent yield.