70083-20-4 Usage
Chemical structure
A heterocyclic compound with a benzoxazole ring fused to a quinazoline ring and a carbonyl group at the 12th position.
Application in medicinal chemistry
Used as a scaffold for developing potential drug candidates due to its diverse pharmacological activities.
Anticancer
Exhibits potential in fighting cancer cells.
Antimicrobial
Demonstrates activity against microorganisms, such as bacteria and fungi.
Anti-inflammatory
Helps reduce inflammation in the body.
Anxiolytic
May have the ability to alleviate anxiety.
Anticonvulsant
Could potentially prevent or reduce the severity of seizures.
Unique structure
The compound's structure allows for versatile properties and makes it a valuable target for chemical synthesis and drug development.
Importance in drug development
Due to its diverse pharmacological activities and unique structure, 12H-[1,3]benzoxazolo[2,3-b]quinazolin-12-one is a promising candidate for the development of new drugs targeting various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 70083-20-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,0,8 and 3 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 70083-20:
(7*7)+(6*0)+(5*0)+(4*8)+(3*3)+(2*2)+(1*0)=94
94 % 10 = 4
So 70083-20-4 is a valid CAS Registry Number.
70083-20-4Relevant articles and documents
Potassium Periodate Mediated Oxidative Cyclodesulfurization toward Benzofused Nitrogen Heterocycles
Duangkamol, Chuthamat,Pattarawarapan, Mookda,Phakhodee, Wong
, p. 1981 - 1990 (2020/07/03)
A convenient oxidative cyclodesulfurization method toward the synthesis of benzofused nitrogen heterocycles using inexpensive and readily available potassium periodate as an oxidant was developed. Upon treating isothiocyanates with ortho -substituted anilines bearing N, N -, N, O -, and N, S -bis-nucleophiles, followed by an intramolecular cyclization of the in situ generated monothioureas, substituted 2-aminobenzazole series were rapidly accessible in good to excellent yields. The protocol can accommodate various substituents on both substrates while allowing more efficient, greener, and operational simpler process relative to other oxidative coupling reactions. Tetracyclic quinazolinone derivatives were also afforded in high yields in a single preparative step and chromatography-free.
