700844-36-6

Basic information

• Product Name: Thieno[3,2-b]pyridine-6-carbonitrile, 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-iodo-
• CAS NO: 700844-36-6
• Molecular Formula: C15H8Cl2IN3OS
• Molecular Weight: 476.125
• Mol File: 700844-36-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Thieno[3,2-b]pyridine-6-carbonitrile, 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-iodo-(CAS DataBase Reference)
• NIST Chemistry Reference: Thieno[3,2-b]pyridine-6-carbonitrile, 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-iodo-(700844-36-6)
• EPA Substance Registry System: Thieno[3,2-b]pyridine-6-carbonitrile, 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-iodo-(700844-36-6)

Safety Data

• Hazardous Substances Data: 700844-36-6(Hazardous Substances Data)

Upstream product

• 83179-01-5 ethyl 7-chlorothieno<3,2-b>pyridine-6-carboxylate 
• 90690-94-1 7-chlorothieno<3,2-b>pyridine-6-carboxylic acid 
• 700844-10-6 7-chlorothieno[3,2-b]pyridine-6-carboxamide 
• 700844-09-3 7-chlorothieno[3,2-b]pyridine-6-carbonitrile 
• 98446-49-2 2,4-dichloro-5-methoxyaniline 
• 700844-17-3 7-chloro-2-iodothieno[3,2-b]pyridine-6-carbonitrile 

Downstream Products

• 700844-69-5 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-[5-(1,3-dioxolan-2-yl)thien-3-yl]thieno[3,2-b]pyridine-6-carbonitrile 
• 700845-16-5 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-[5-(1,3-dioxolan-2-yl)thien-2-yl]thieno[3,2-b]pyridine-6-carbonitrile 
• 700844-65-1 7-[ (2, 4-dichloro-5-methoxyphenyl) amino]-2-[ (trimethylsilyl) ethynyl] thieno [3,2-b] pyridine-6-carbonitrile 
• 700844-56-0 2-(1-benzofuran-2-yl)-7-[(2, 4-dichloro-5-methoxyphenyl) amino] thieno [3,2-b] pyridine-6-carbonitrile 
• 700844-53-7 7-[ (2, 4-dichloro-5-methoxyphenyl) amino]-2-[ (4-methoxyphenyl) ethynyl] thieno [3,2-b] pyridine-6-carbonitrile 
• 700844-54-8 7-[(2, 4-dichloro-5-methoxyphenyl) amino]-2-(pyridin-2-ylethynyl) thieno [3,2-b] pyridine-6-carbonitrile 
• 700844-68-4 7-[(2, 4-dichloro-5-methoxyphenyl) amino]-2-(pyridin-3-ylethynyl) thieno [3,2-b] pyridine-6-carbonitrile 
• 700844-46-8 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-(4-formylphenyl)thieno[3,2-b]pyridine-6-carbonitrile 
• 700844-51-5 4-{6-cyano-7-[(2,4-dichloro-5-methoxyphenyl)amino]thieno[3,2-b]pyridin-2-yl}benzoic acid 
• 700844-57-1 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-(3-formylphenyl)thieno[3,2-b]pyridine-6-carbonitrile 
• 700844-55-9 7-[ (2, 4-dichloro-5-methoxyphenyl) amino]-2-[3-(dimethylamino) prop-1-ynyl] thieno [3,2-b] pyridine-6-carbonitrile 
• 700845-18-7 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-(5-formylthien-2-yl)thieno[3,2-b]pyridine-6-carbonitrile 

Relevant articles and documents

Identification of 7-phenylaminothieno-[3,2-b]pyridine-6-carbonitriles as a new class of Src kinase inhibitors

We disclose here a new class of kinase inhibitors, obtained by replacing the phenyl ring of a 3-quinolinecarbonitrile system with a thiophene ring. When suitably substituted, the resultant 7-phenylaminothieno[3,2-b]pyridine-6- carbonitrile analogues show

THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AND THIENO[2,3-b]PYRIDINE-5-CARBONITRILES AS PROTEIN KINASE INHIBITORS

This invention provides compounds of Formula (1 a) - (1f) wherein:X, R1, and R2 are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.