700844-75-3Relevant articles and documents
Synthesis and Src kinase inhibitory activity of 2-phenyl- and 2-thienyl-7-phenylaminothieno[3,2-b]pyridine-6-carbonitriles
Boschelli, Diane H.,Wu, Biqi,Sosa, Ana Carolina Barrios,Durutlic, Haris,Chen, Joan J.,Wang, Yan,Golas, Jennifer M.,Lucas, Judy,Boschelli, Frank
, p. 3891 - 3902 (2007/10/03)
2-Phenyl-7-phenylaminothieno[3,2-b]pyridine-6-carbonitriles were recently reported to be inhibitors of Src kinase activity. In this study we present structure-activity relationships for additional thieno[3,2-b]pyridine-6- carbonitriles, modifying the subs
THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AND THIENO[2,3-b]PYRIDINE-5-CARBONITRILES AS PROTEIN KINASE INHIBITORS
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Page 116, (2010/02/07)
This invention provides compounds of Formula (1 a) - (1f) wherein:X, R1, and R2 are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.