700845-54-1

Basic information

• Product Name: 7-[(2,4-dichlorophenyl)amino]-3-(4-formylphenyl)thieno[3,2-b]pyridine-6-carbonitrile
• Synonyms: 7-[(2,4-dichlorophenyl)amino]-3-(4-formylphenyl)thieno[3,2-b]pyridine-6-carbonitrile
• CAS NO: 700845-54-1
• Molecular Weight: 424.31
• Mol File: 700845-54-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 7-[(2,4-dichlorophenyl)amino]-3-(4-formylphenyl)thieno[3,2-b]pyridine-6-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(2,4-dichlorophenyl)amino]-3-(4-formylphenyl)thieno[3,2-b]pyridine-6-carbonitrile(700845-54-1)
• EPA Substance Registry System: 7-[(2,4-dichlorophenyl)amino]-3-(4-formylphenyl)thieno[3,2-b]pyridine-6-carbonitrile(700845-54-1)

Safety Data

• Hazardous Substances Data: 700845-54-1(Hazardous Substances Data)

Upstream product

• 700844-17-3 7-chloro-2-iodothieno[3,2-b]pyridine-6-carbonitrile 
• 700844-10-6 7-chlorothieno[3,2-b]pyridine-6-carboxamide 
• 700844-09-3 7-chlorothieno[3,2-b]pyridine-6-carbonitrile 
• 83179-01-5 ethyl 7-chlorothieno<3,2-b>pyridine-6-carboxylate 
• 87199-17-5 4-formylphenylboronic acid, 
• 700845-41-6 7-[(2,4-dichlorophenyl)amino]-2-iodothieno[3,2-b]pyridine-6-carbonitrile 
• 90690-94-1 7-chlorothieno<3,2-b>pyridine-6-carboxylic acid 

Relevant articles and documents

Thieno[3,2-b]pyridine-6-carbonitriles and thieno[2,3-b]pyridine-5-carbonitriles as protein kinase inhibitors

This invention provides compounds of Formula (1a)-(1f), II wherein: X, m, n, q, R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Q, Z, Z′, Z′″, Z″ and J are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, neuropathic pain, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.

Identification of 7-phenylaminothieno-[3,2-b]pyridine-6-carbonitriles as a new class of Src kinase inhibitors

We disclose here a new class of kinase inhibitors, obtained by replacing the phenyl ring of a 3-quinolinecarbonitrile system with a thiophene ring. When suitably substituted, the resultant 7-phenylaminothieno[3,2-b]pyridine-6- carbonitrile analogues show