70132-14-8

Basic information

• Product Name: EC 1.4.3.14
• Synonyms: LYSINE OXIDASE;L-LYSINE: OXYGEN OXIDOREDUCTASE [DEAMINATING];EC 1.4.3.14;lysine oxidase from trichoderma viride
• CAS NO: 70132-14-8
• Molecular Weight: 0
• Mol File: 70132-14-8.mol
• Article Data: 0

Chemical Properties

• Appearance: /lyophilized powder
• Storage Temp.: 2-8°C
• CAS DataBase Reference: EC 1.4.3.14(CAS DataBase Reference)
• NIST Chemistry Reference: EC 1.4.3.14(70132-14-8)
• EPA Substance Registry System: EC 1.4.3.14(70132-14-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 70132-14-8(Hazardous Substances Data)

Usage

Description

EC 1.4.3.14, also known as lysine oxidase, is a homodimeric flavoenzyme derived from Trichoderma viride with a molecular mass of 112 kDa. It is stable at 65°C and exhibits high specificity for the L-lysine substrate. The enzyme consists of FAD-binding, substrate binding, and a helical domain with a distinct active site funnel.

Uses

Used in Biotechnology Industry:
EC 1.4.3.14 is used as a key enzyme in the preparation of luminescent biochips for various applications, such as biosensing, diagnostics, and research.
Used in Diagnostics:
Lysine oxidase is employed in the development of diagnostic tools, particularly in the detection and analysis of lysine-containing compounds, which can be crucial in understanding various biological processes and diseases.
Used in Research:
The enzyme plays a significant role in research, particularly in the study of enzyme mechanisms, protein-protein interactions, and the development of novel biocatalytic systems.
Used in Pharmaceutical Industry:
Lysine oxidase can be utilized in the development of new drugs and drug delivery systems, taking advantage of its specificity and stability to target specific biological pathways or molecules.

Biochem/physiol Actions

Lysine Oxidase from Trichoderma viride catalyzes the formation of α-keto- ε-aminocaproate by the oxidative deamination of L-lysine. It displays anti-tumor functionality in cancer leukaemic cells. It is a tumor suppressor for squamous cell, fibroblast, ovarian and gastric tumors. Lysine oxidase also plays key role in connective tissue structural integrity and embryo development.