70205-05-9

Basic information

• Product Name: 5-formyl-2-methoxyphenyl methanesulfonate
• Synonyms: 5-formyl-2-methoxyphenyl methanesulfonate
• CAS NO: 70205-05-9
• Molecular Weight: 230.241
• Mol File: 70205-05-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 5-formyl-2-methoxyphenyl methanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 5-formyl-2-methoxyphenyl methanesulfonate(70205-05-9)
• EPA Substance Registry System: 5-formyl-2-methoxyphenyl methanesulfonate(70205-05-9)

Safety Data

• Hazardous Substances Data: 70205-05-9(Hazardous Substances Data)

Upstream product

• 621-59-0 isovanillin 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 1428848-06-9 (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-(2-(4-methoxy-3-(methylsulfonyloxy)benzoylthio)-acetoxy)ethyl)pyridine 1-oxide 
• 1428848-07-0 2-(4-methoxy-3-(methylsulfonyloxy)benzoylthio)acetic acid 
• 1100185-47-4 methanesulfonic acid 5-((E)-2-formyl-3-methylbut-1-enyl)-2-methoxyphenyl ester 
• 1100185-49-6 methanesulfonic acid 5-((Z)-2-formyl-3-methylbut-1-enyl)-2-methoxyphenyl ester 
• 65982-86-7 4-methoxy-3-(methylsulfonyloxy)benzoic acid 
• 910622-15-0 ethyl 4-(3-mesyloxy-4-methoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate 
• 910622-14-9 ethyl 2-chloromethyl-4-(3-mesyloxy-4-methoxyphenyl)-6,7-dimethoxyquinoline-3-carboxylate 
• 910622-12-7 2-acetamino-3'-mesyloxy-4,4',5-trimethoxybenzophenone 

Relevant articles and documents

Syntheses of metabolites of ethyl 4-(3,4-dimethoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (TAK-603)

Convenient and efficient syntheses of ethyl 4-(3-hydroxy-4-methoxyphenyl)-6,7-dimethoxy-2-(1,2,4-triazol-1-ylmethyl)quinoline-3-carboxylate (1d) and 10-(3,4-dimethoxyphenyl)-7,8-dimethoxy-2H-pyridazino[4,5-b]quinolin-1-one (1e), metabolites of TAK-603 (1)

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1-phenyl-2-pyridinyl alkyl alcohols, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

DERIVATIVES OF 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOLS AS PHOSPHODIESTERASE INHIBITORS

The invention relates to inhibitors of the phosphodiesterase 4 (PDE4) enzyme. More particularly, the invention relates to compounds that are derivatives of 1-phenyl-2-pyridinyl alkyl alcohols of formula (I), methods of preparing such compounds, compositio