70242-11-4

Basic information

• Product Name: 2-bromo-3,4,5-trimethoxy-benzoyl chloride
• Synonyms: 2-bromo-3,4,5-trimethoxy-benzoyl chloride
• CAS NO: 70242-11-4
• Molecular Weight: 309.544
• Mol File: 70242-11-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-bromo-3,4,5-trimethoxy-benzoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-3,4,5-trimethoxy-benzoyl chloride(70242-11-4)
• EPA Substance Registry System: 2-bromo-3,4,5-trimethoxy-benzoyl chloride(70242-11-4)

Safety Data

• Hazardous Substances Data: 70242-11-4(Hazardous Substances Data)

Upstream product

• 23346-82-9 2-bromo-3,4,5-trimethoxybenzoic acid 

Downstream Products

• 82463-70-5 2-bromo-3,4,5-trimethoxy-N-methylbenzamide 
• 23434-97-1 thalactamine 
• 1432372-30-9 6,7,8-trimethoxy-2-methyl-2,5-dihydro-1H-benzo[c]azepin-1-one 
• 1432372-33-2 6,7,8-trimethoxy-2-methyl-2,3-dihydro-1H-benzo[c]azepin-1-one 
• 1386273-49-9 C₁₄H₁₉NO₄ 
• 1432371-71-5 2-bromo-N-cyclopropyl-3,4,5-trimethoxy-N-methylbenzamide 
• 1369582-03-5 3-(2-bromo-3,4,5-trimethoxybenzoyl)-5-methoxy-1H-indole 
• 1369581-97-4 3-(2-bromo-3,4,5-trimethoxybenzoyl)-1-methyl-1H-indole 
• 1369582-02-4 3-(2-bromo-3,4,5-trimethoxybenzoyl)-1H-indole 
• 102554-21-2 3-(2-bromo-3,4,5-trimethoxy-phenyl)-1-(3,4-dimethoxy-phenyl)-propan-1-one 
• 102159-72-8 2-bromo-3,4,5,3',4'-pentamethoxy-trans-chalcone 
• 911822-61-2 (S)-2,2'-bis(2-bromo-3,4,5-trimethoxybenzoyl)-1,1'-binaphthalene 
• 35274-53-4 2-bromo-3,4,5-tri-methoxybenzaldehyde 

Relevant articles and documents

Palladium-catalyzed ring-opening of cyclopropyl benzamides: Synthesis of benzo[c]azepine-1-ones via C(sp3)-H functionalization

A variety of difficult to obtain benzo[c]azepine-1-ones are synthesized via a novel palladium-catalyzed, silver-promoted intramolecular cyclization of cyclopropyl benzamides. This biologically important class of molecules is prepared in an efficient and high-yielding manner from easily accessible starting materials. Both aryl bromides and iodides are effective substrates for the transformation. Mechanistic studies indicate that the reaction proceeds through a cyclopropyl C(sp3)-H cleavage step, followed by ring-opening, deprotonation, and reductive elimination.

OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY AND PROCESS FOR PRODUCING -AMINO ACID AND DERIVATIVE THEREOF WITH THE SAME

The present invention provides a chiral phase-transfer catalyst of the following formula (I): The compound (I) can be produced by reacting a 2,2'-dimethylene bromide-1,1'-biphenyl derivative, which can be produced through comparatively small number of steps, with an easily available secondary amine.