70243-84-4

Basic information

• Product Name: Ethanone, 1-[2-(1-pyrrolidinyl)phenyl]-
• CAS NO: 70243-84-4
• Molecular Formula: C12H15NO
• Molecular Weight: 189.257
• Mol File: 70243-84-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-[2-(1-pyrrolidinyl)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[2-(1-pyrrolidinyl)phenyl]-(70243-84-4)
• EPA Substance Registry System: Ethanone, 1-[2-(1-pyrrolidinyl)phenyl]-(70243-84-4)

Safety Data

• Hazardous Substances Data: 70243-84-4(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 445-27-2 2'-Fluoroacetophenone 
• 1443005-29-5 C₁₅H₂₁NSi 
• 615-43-0 2-iodophenylamine 
• 87698-81-5 1‐(2‐bromophenyl)pyrrolidine 
• 615-36-1 2-bromoaniline 
• 1438277-47-4 1-(2-ethynylphenyl)pyrrolidine 
• 110-52-1 1,4-dibromo-butane 
• 551-93-9 2-aminoacetophenone 

Downstream Products

• 1362296-18-1 C₁₂H₁₅ClN₂ 
• 1092982-57-4 4-(4-bromophenyl)-5-methyl-1,2,3,4a,4,5-hexahydropyrrolo[1,2-a]quinazoline 
• 117607-67-7 2-{1'-[2'-(pyrrolidin-1''-yl)phenyl]ethylidene}propanedinitrile 
• 135064-68-5 (Z)-2-Cyano-3-(2-pyrrolidin-1-yl-phenyl)-but-2-enoic acid ethyl ester 
• 135064-82-3 (E)-2-Cyano-3-(2-pyrrolidin-1-yl-phenyl)-but-2-enoic acid ethyl ester 

Relevant articles and documents

Diastereoselective synthesis of dihydro-quinolin-4-ones by a borane-catalyzed redox-neutral endo-1,7-hydride shift

The borane-catalyzed synthesis of dihydroquinoline-4-ones is developed. The amino-substituted chalcones undergo a 1,7-hydride shift upon Lewis acid activation to form a zwitterionic iminium enolate, which collapses to the dihydroquinoline-4-one scaffold.

Metal-free oxidation/C(sp3)iH functionalization of unactivated alkynes using pyridine-N-oxide as the external oxidant

Externally yours: 2,3-Dihydroquinolin-4(1H)-ones are obtained in moderate to good yields (40-84 %, see scheme) in a metal-free oxidation/C(sp 3)iH functionalization of unactivated aryl alkynes. 2,6-Dichloropyridine-N-oxide is used as an external oxidant. In the reaction, a Bronsted acid, not a metal, plays a key role in the triple CiC bond activation. Copyright

NOVEL APPLICATIONS OF THE "t-AMINO EFFECT" IN HETEROCYCLIC CHEMISTRY. SYNTHESIS OF A PYRROLOQUINAZOLINE AND 5H-PYRROLOBENZOTHIAZINES

1-(1-Pyrrolidinyl)benzenes substituted with an imino- or an in situ generated thiocarbonyl group in the 2-position rearrange upon heating to quinazoline and benzothiazine derivatives, respectively.