7026-45-1Relevant articles and documents
A one-pot preparation of 1-benzyl-2'-deoxyinosine from ionized 2'-deoxyinosine
Moon,Kim
, p. 1135 - 1143 (2007/10/03)
A simple and one step synthetic method for the formation of 1-benzyl-2'-deoxyinosine was developed by direct benzylation of ionized 2'-deoxyinosine. Treatment of 2'-deoxyinosine, in the presence of NaOH, with benzyl bromide in 2,2,2-trifluoroethanol (TFE) or N,N-dimethylaetamide (DMA) gave 1-benzyl-2'-deoxyinosine in 35% and 80% yields, respectively.