70288-75-4

Basic information

• Product Name: Phenylalanine-N-carboxylic acid dimethyl ester
• Synonyms: Phenylalanine-N-carboxylic acid dimethyl ester
• CAS NO: 70288-75-4
• Molecular Formula: C₁₂H₁₅NO₄
• Molecular Weight: 237.25
• Mol File: 70288-75-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 377.4°C at 760 mmHg
• Flash Point: 182.1°C
• Appearance: /
• Density: 1.16g/cm³
• Vapor Pressure: 6.76E-06mmHg at 25°C
• Refractive Index: 1.512
• CAS DataBase Reference: Phenylalanine-N-carboxylic acid dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phenylalanine-N-carboxylic acid dimethyl ester(70288-75-4)
• EPA Substance Registry System: Phenylalanine-N-carboxylic acid dimethyl ester(70288-75-4)

Safety Data

• Hazardous Substances Data: 70288-75-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H15NO4/c1-16-11(14)10(13-12(15)17-2)8-9-6-4-3-5-7-9/h3-7,10H,8H2,1-2H3,(H,13,15)

Upstream product

• 150-30-1 Phenylalanine 
• 67-56-1 methanol 
• 590-28-3 potassium cyanate 
• 70288-60-7 methyl 2-bromo-3-phenylpropionate 
• 79-22-1 methyl chloroformate 
• 5619-07-8 methyl 2-amino-3-phenylpropanoate hydrochloride 
• 135517-12-3 methyl (2Z)-2-[(methoxycarbonyl)amino]-3-phenylprop-2-enoate 

Downstream Products

• 27172-85-6 phenylalanine methyl ester hydrochloride 
• 153576-01-3 methyl N-carbomethoxy-α,β-didehydrophenylalaninate 

Relevant articles and documents

A polymer-supported rhodium catalyst that functions in polar protic solvents

(matrix presented) Highly cross-linked macroporous polymers are excellent supports for heterogenizing rhodium alkene hydrogenation and hydroboration catalysts. The permanent pore structure of the support enables high conversions and excellent yields with minimal workup (filtering). These heterogenized catalysts can be reused, and due to the permanent pore structure, they function in a broad range of solvents including polar protic. Control experiments reveal that catalysis occurs exclusively within the polymer matrix, and not due to leached catalyst.

Aminosaeuren, I. Darstellung von Aminosaeuren aus Halogencarbonsaeure-alkylestern mit Alkalimetallcyanaten

α- and ω-halo- as well as α,ω-dihalocarboxylic alkyl esters react with potassium cyanate in the presence of alcohol at 80 - 120 deg C in dipolar aprotic solvents to yield α- and ω-(alkoxycarbonylamino)- and α,ω-bis(alkoxycarbonylamino)carboxylic alkyl esters, respectively, in good yields.Hydrolytic cleavage of these mono- or diurethanes with an aqueous solution of hydrochloric acid/formic acid leads to the corresponding amino acid hydrochlorides in nearly quantitative yields.