70374-27-5 Usage
Chemical structure
Thieno-thiazine ring system with a chloro and hydroxyl group attached, as well as a pyridine substituent
Activity
Potent and selective antagonist of the dopamine D3 receptor
Potential therapeutic uses
Treatment of neurological disorders such as schizophrenia and drug addiction
Importance
Unique structure and functional properties make it an important target for pharmaceutical research and drug development
Check Digit Verification of cas no
The CAS Registry Mumber 70374-27-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,3,7 and 4 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 70374-27:
(7*7)+(6*0)+(5*3)+(4*7)+(3*4)+(2*2)+(1*7)=115
115 % 10 = 5
So 70374-27-5 is a valid CAS Registry Number.
70374-27-5Relevant articles and documents
Thiazine derivatives
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, (2008/06/13)
Anti-inflammatory, analgesic, anti-rheumatic and anti-thrombotic thienothiazine derivatives having the formula STR1 wherein A together with the two carbon atoms forms the group STR2 and the dotted line indicates the double bond present in the first and last thieno structures above, R1 is lower alkyl, R2 is the radical of an aromatic heterocycle with 1 to 4 hetero atoms optionally substituted by one or two lower alkyl groups, or a phenyl radical optionally substituted by halogen, hydroxy, lower alkyl, trifluoromethyl or lower alkoxy, R3 is halogen and R3' is hydrogen or halogen, and pharmaceutically acceptable salts thereof are described.
