7038-15-5Relevant articles and documents
72. Synthesis of 2-Substituted and 2,3-Disubstituted Alkyl-and Aryl-thiophenes and Related 2,3-Anellated Thiophene Derivatives, Using Ketones and Carbonodithioic Acid O-Ethyl S-(2-Oxoethyl) Ester as the Building Blocks
Waldvogel, Erwin
, p. 907 - 912 (2007/10/02)
A simple method to synthesize 2-substituted and 2,3-disubstituted alkyl- and aryl-thiophenes as well as related 2,3-anellated thiophenes 6, starting from ketones 1 as C2-fragment and the S-protected carbonodithionic-acid derivative 3 as a C2S-fragment is described.The aldols 4 are intermediates of the two step process.