70424-54-3

Basic information

• Product Name: castelanone
• Synonyms: castelanone;11β,20-Epoxy-1β,11,12α-trihydroxy-15β-(3-methyl-1-oxobutoxy)picras-3-ene-2,16-dione;2,16-Dioxo-11β,20-epoxypicrasa-3-ene-1β,11,12α,15β-tetrol 15-(3-methylbutanoate)
• CAS NO: 70424-54-3
• Molecular Formula: C25H34O9
• Molecular Weight: 478.53206
• Mol File: 70424-54-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 672.3°C at 760 mmHg
• Flash Point: 226.2°C
• Appearance: /
• Density: 1.38g/cm³
• Vapor Pressure: 5.94E-21mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: castelanone(CAS DataBase Reference)
• NIST Chemistry Reference: castelanone(70424-54-3)
• EPA Substance Registry System: castelanone(70424-54-3)

Safety Data

• Hazardous Substances Data: 70424-54-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C25H34O9/c1-10(2)6-16(27)34-18-17-12(4)19(28)25(31)22-23(5)13(11(3)7-14(26)20(23)29)8-15(33-21(18)30)24(17,22)9-32-25/h7,10,12-13,15,17-20,22,28-29,31H,6,8-9H2,1-5H3/t12-,13+,15-,17-,18-,19-,20-,22-,23-,24+,25+/m1/s1

Upstream product

• 83137-29-5 C₃₄H₅₆O₉Si₂ 
• 4616-50-6 chaparrin 
• 83117-01-5 C₃₂H₅₆O₇Si₂ 
• 83137-28-4 C₃₅H₆₄O₇Si₃ 
• 83117-07-1 C₃₄H₅₈O₉Si₂ 
• 83117-03-7 C₃₅H₆₄O₈Si₃ 
• 83117-04-8 C₄₀H₇₂O₉Si₃ 
• 83137-29-5 C₃₄H₅₆O₉Si₂ 

Relevant articles and documents

Biologically active quassinoids : synthetic methodology for the conversion of chaparrin into glaucarubolone esters and quassinoid analogs1 1 For previous paper in this series see: C. Moretti, S. Bhatnagar, J.C. Beloeil and J. Polonsky, J. Nat. Prods., 49, 440 (1986)

Biologically inactive but easily available chaparrin 2a has been converted into potent antileukemic C-15 esters of glaucarubolone 2b and quassinoid analogs in which the C-15 ester side chain has been replaced by an alkyl or alkenyl group.The synthetic methodology developed has been applied to the preparation of C-15 ester derivatives 15, 16, 17 and quassinoid analogs 12, 13 and 14.