70485-98-2

Basic information

• Product Name: N,N-Diisopropyl-3-amino-1-phenyl-prop-2-en-1-on (E)
• Synonyms: N,N-Diisopropyl-3-amino-1-phenyl-prop-2-en-1-on (E)
• CAS NO: 70485-98-2
• Molecular Weight: 231.338
• Mol File: 70485-98-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N,N-Diisopropyl-3-amino-1-phenyl-prop-2-en-1-on (E)(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-Diisopropyl-3-amino-1-phenyl-prop-2-en-1-on (E)(70485-98-2)
• EPA Substance Registry System: N,N-Diisopropyl-3-amino-1-phenyl-prop-2-en-1-on (E)(70485-98-2)

Safety Data

• Hazardous Substances Data: 70485-98-2(Hazardous Substances Data)

Upstream product

• 2579-22-8 Phenylpropargyl aldehyde 
• 108-18-9 diisopropylamine 
• 3592-47-0 Benzaldehyde-d 
• 75-20-7 calcium carbide 
• 100-52-7 benzaldehyde 

Downstream Products

• 3506-54-5 3-(diethylamino)-1-phenylprop-2-en-1-one 
• 4452-12-4 1-phenyl-3-(piperidin-1-yl)prop-2-en-1-one 
• 14376-90-0 3-(benzylamino)-1-phenylprop-2-en-1-one 
• 19134-41-9 3-(butylamino)-1-phenylprop-2-en-1-one 
• 1215-50-5 1-phenyl-3-(phenylamino)prop-2-en-1-one 
• 15753-58-9 1-phenyl-3-(pyridin-3-ylamino)prop-2-en-1-one 
• 3453-00-7 diethyl benzoylmethylphosphonate 

Relevant articles and documents

Highly regioselective synthesis of cis-β-enaminones by 1,4-addition of propiolaldehydes

A convenient one-pot strategy for the regioselective synthesis of cis-β-enaminones has been developed via the condensation of propiolaldehydes and amines in EtOH. This process has opened a new synthetic route to enamines in good yield. A possible reaction mechanism involving a Michael addition/enol tautomerization via a six-membered ring transition state is proposed.

Acetylide Ion (C22-) as a synthon to link electrophiles and nucleophiles: A simple method for enaminone synthesis

Friendly competition: A three-component reaction system composed of calcium carbide, an aryl aldehyde, and an amine gave enaminones or propargylamines (see picture) in a predictable manner through competitive pathways. The system enables the cost-efficient synthesis of a variety of enaminones from readily accessible small molecules and demonstrates the versatility of the acetylide ion, which can be used to bridge electrophiles and nucleophiles. Copyright