704910-07-6Relevant articles and documents
Peptide synthesis in water IV. Preparation of N- ethanesulfonylethoxycarbonyl (Esc) amino acids and their application to solid phase peptide synthesis
Hojo, Keiko,Maeda, Mitsuko,Smith, Timothy J.,Kita, Eriko,Yamaguchi, Fumie,Yamamoto, Sachiko,Kawasaki, Koichi
, p. 422 - 427 (2007/10/03)
A new N-protecting group, ethanesulfonylethoxycarbonyl (Esc), was designed to perform peptide synthesis in both aqueous and organic solvents. Esc-amino acids were prepared by the reaction of Esc-Cl and amino acids. Although Esc-Cl was a highly reactive re