70499-13-7

Basic information

• Product Name: 7-CHLORO-2-METHYL-4(1H)-QUINOLINONE
• Synonyms: 7-CHLORO-4-HYDROXY-2-METHYLQUINOLINE;7-CHLORO-2-METHYL-4(1H)-QUINOLINONE;7-chloro-2-methyl-4-quinolone;7-Chloro-2-methylquinolin-4(1H)-one
• CAS NO: 70499-13-7
• Molecular Formula: C₁₀H₈ClNO
• Molecular Weight: 193.63
• EINECS: 274-629-6
• Mol File: 70499-13-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-CHLORO-2-METHYL-4(1H)-QUINOLINONE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-CHLORO-2-METHYL-4(1H)-QUINOLINONE(70499-13-7)
• EPA Substance Registry System: 7-CHLORO-2-METHYL-4(1H)-QUINOLINONE(70499-13-7)

Safety Data

• Hazardous Substances Data: 70499-13-7(Hazardous Substances Data)

Upstream product

• 141-97-9 ethyl acetoacetate 
• 108-42-9 3-chloro-aniline 

Relevant articles and documents

Microwave-assisted Synthesis of 2-methyl-4-quinolinones via combes synthesis catalyzed by acidic resin under solvent-free condition

A simple and efficient method for the synthesis of 2-methylquinolin-4(1H)- one derivatives using NKC-9-resin as reusable eco-friendly catalyst via Combes cyclization under solvent-free and microwave irradiation conditions is described. The quinolines were obtained in high yields and in short reaction times.

Synthesis of a quinolone library from ynones

A library of 72 quinolones was synthesized from substituted anthranilic acids, using ynone intermediates. These masked β-dicarbonyl synthons allowed cyclization under milder conditions than previously reported quinolone syntheses.