705-06-6

Basic information

• Product Name: 1-butylpyrimidine-2,4(1H,3H)-dione
• CAS NO: 705-06-6
• Molecular Formula: C₈H₁₂N₂O₂
• Molecular Weight: 168.1931
• Mol File: 705-06-6.mol
• Article Data: 6

Chemical Properties

• Density: 1.118g/cm³
• Refractive Index: 1.494
• CAS DataBase Reference: 1-butylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-butylpyrimidine-2,4(1H,3H)-dione(705-06-6)
• EPA Substance Registry System: 1-butylpyrimidine-2,4(1H,3H)-dione(705-06-6)

Safety Data

• Hazardous Substances Data: 705-06-6(Hazardous Substances Data)

Usage

General Description

1-Butylpyrimidine-2,4(1H,3H)-dione is a chemical compound with the molecular formula C9H12N2O2. It is an organic compound that belongs to the class of pyrimidine-2,4(1H,3H)-dione. It is a solid white powder at room temperature and is insoluble in water. 1-butylpyrimidine-2,4(1H,3H)-dione is used in various industrial and research applications, including as a building block in organic synthesis and as a pharmaceutical intermediate. Its chemical structure and properties make it suitable for use in the development of new drugs and in the production of other organic compounds. Additionally, it is important to handle and store this chemical safely as it may be harmful if ingested, inhaled, or comes into contact with skin or eyes.

Upstream product

• 7424-91-1 methyl 3,3-dimethoxypropionate 
• 592-31-4 1-butyl-urea 
• 41365-74-6 3,3-diethoxypropionic amide 
• 111-36-4 n-butyl isocyanide 
• 109-65-9 1-bromo-butane 
• 66-22-8 uracil 
• 71-36-3 butan-1-ol 

Downstream Products

• 905854-83-3 N³-benzoyl-N¹-n-butyl-5-iodouracil 
• 905854-85-5 3-benzoyl-1-butyl-5-[2-(5,6-dihydro-[1,3]dithiolo[4,5-b][1,4]dithiin-2-ylidene)-[1,3]dithiol-4-yl]-1H-pyrimidine-2,4-dione 

Relevant articles and documents

Hydrogen-bonded charge-transfer complexes of TTF containing a uracil moiety: Crystal structures and electronic properties of the hydrogen cyananilate and TCNQ complexes

(matrix presented) A novel TTF-based donor with a uracil moiety, TTF-(1-n-butyluracil-5-yl) (TnbU), was synthesized. Crystal structures of both TnbU and the charge-transfer complex of TnbU-hydrogen cyananilate possess complementary double hydrogen bonds t

Water-induced gel formation of an oleanlic acid-adenine conjugate and the effects of uracil derivative on the gel stability

The conjugate of oleanlic acid with adenine was synthesized and it could be gelled in mixed solvents of THF and water, but no gel was formed in the single organic solvent. The self-aggregation behaviour and physical properties of the organogel were characterized by 1H NMR, FT-IR, and scanning electron microscopy. The morphology and the stability of the gel were remarkably affected by the uracil derivative through destroying hydrogen-bonding.

Improved One-Step Procedure for the Preparation of 1-Substituted and 1,3-Disubstituted Uracils and 2-Thiouracils

A convenient one-pot procedure for the synthesis of 1-substituted and 1,3-disubstituted uracils and 2-thiouracils consists of acylation of ureas or thioureas with methyl 3,3-dimethoxypropanoate in the presence of a strong base, and acidic work-up.The yields range from 36 to 99percent.In all cases, only one regioisomer is isolated.