70578-24-4 Usage
Description
Yunnaconitine is a deiterpene alkaloid metabolite of Aconitine (A189875), a neurotoxin that is known for its cytotoxic activity in human leukemic cells. It functions by binding to and activating tetrodotoxin-sensitive Na+ channels, which leads to the prolongation of the opening of the sodium-ion channel by suppressing conformational changes.
Uses
Used in Pharmaceutical Industry:
Yunnaconitine is used as a cytotoxic agent for its ability to target and potentially eliminate cancer cells, particularly in the context of human leukemia. Its interaction with sodium-ion channels makes it a compound of interest for the development of novel cancer treatments.
Used in Neurological Research:
As a neurotoxin that affects sodium-ion channels, Yunnaconitine can be utilized in research aimed at understanding the role of these channels in neurological disorders and the development of targeted therapies for conditions related to ion channel dysfunction.
Check Digit Verification of cas no
The CAS Registry Mumber 70578-24-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,7 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 70578-24:
(7*7)+(6*0)+(5*5)+(4*7)+(3*8)+(2*2)+(1*4)=134
134 % 10 = 4
So 70578-24-4 is a valid CAS Registry Number.
InChI:InChI=1/C35H49NO11/c1-8-36-16-32(17-41-3)22(38)13-23(43-5)35-21-14-33(40)24(44-6)15-34(47-18(2)37,26(29(35)36)27(45-7)28(32)35)25(21)30(33)46-31(39)19-9-11-20(42-4)12-10-19/h9-12,21-30,38,40H,8,13-17H2,1-7H3/t21-,22-,23+,24+,25-,26+,27+,28-,29?,30-,32+,33+,34-,35+/m1/s1
