70585-54-5 Usage
General Description
8-Quinolinecarboxylic acid, 7-methyl- (9CI) is a chemical compound with the molecular formula C11H9NO2. It is a derivative of quinoline and belongs to the class of carboxylic acids. 8-Quinolinecarboxylicacid,7-methyl-(9CI) is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical formulations. It has also been studied for its potential biological activities, including antimicrobial, antifungal, and antiparasitic properties. Additionally, 8-Quinolinecarboxylic acid, 7-methyl- (9CI) is used in research and development as a reagent for chemical reactions and as a reference standard for analytical purposes. Overall, this compound plays a crucial role in the synthesis of pharmaceuticals and has potential applications in various fields of science and technology.
Check Digit Verification of cas no
The CAS Registry Mumber 70585-54-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,8 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 70585-54:
(7*7)+(6*0)+(5*5)+(4*8)+(3*5)+(2*5)+(1*4)=135
135 % 10 = 5
So 70585-54-5 is a valid CAS Registry Number.
70585-54-5Relevant articles and documents
Catalytic formation of ketones from unactivated esters through rhodium chelation-assisted C-O bond activation
Wang, Jingjing,Zuo, Sujing,Chen, Weiqiang,Zhang, Xinrui,Tan, Kaixin,Tian, Yun,Wang, Jianhui
, p. 8217 - 8231 (2013/09/24)
A new method for building aryl aryl ketones containing heterocyclic rings through chelation-assisted C-O bond activation catalyzed by a rhodium complex has been developed. In this reaction, methyl quinoline-8-carboxylate, methyl quinoxaline-5-carboxylate, and their derivatives were reacted with an excess amount of a substituted phenyl boronic acid in the presence of a rhodium(I) complex to give substituted phenyl(quinolin-8-yl)methanone, phenylquinoxalin-5- ylmethanone, and their derivatives in medium to high yields. The current method offers a highly favorable synthetic pathway to efficiently build related drugs with an 8-benzoylquinoline core structure. This method may prove especially valuable for medicinal chemists for the late-stage introduction of versatile ketone moieties into complex scaffolds for diversity-oriented synthetic strategies.
