70590-32-8 Usage
General Description
N-(5-CHLORO-1H-BENZIMIDAZOL-2-YL)GUANIDINE, also known as guanfacine, is a chemical compound that is commonly used as a medication to treat attention deficit hyperactivity disorder (ADHD) and hypertension. It belongs to the class of medications known as alpha-2 adrenergic agonists, which work by affecting certain chemicals in the brain and blood vessels. Guanfacine is believed to help improve attention, reduce impulsivity and hyperactivity, and lower blood pressure by acting on certain receptors in the brain and blood vessels. It is available in different forms such as tablets and extended-release tablets and is typically taken orally. N-(5-CHLORO-1H-BENZIMIDAZOL-2-YL)GUANIDINE has been found to be effective in managing the symptoms of ADHD and hypertension in both children and adults, and is generally well-tolerated with potential side effects including drowsiness, dizziness, and dry mouth.
Check Digit Verification of cas no
The CAS Registry Mumber 70590-32-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,5,9 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 70590-32:
(7*7)+(6*0)+(5*5)+(4*9)+(3*0)+(2*3)+(1*2)=118
118 % 10 = 8
So 70590-32-8 is a valid CAS Registry Number.
70590-32-8Relevant articles and documents
Method of inhibiting the advanced glycosylation of proteins using 1,2-disubstituted-benzimidazoles
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, (2008/06/13)
The present invention relates to compositions and methods for inhibiting nonenzymatic cross-linking (protein aging). Accordingly, composition is disclosed which comprises 1,2-disubstituted benzimidazoles capable of inhibiting the formation of advanced glycosylation endproducts of target proteins by reacting with the carbonyl moiety of the early glycosylation product of such target proteins formed by their initial glycosylation. The method comprises contacting the target protein with the composition. Both industrial and therapeutic applications for the invention are envisioned, as food spoilage and animal protein aging can be treated.
