70591-70-7

Basic information

• Product Name: 3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine
• Synonyms: 3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine
• CAS NO: 70591-70-7
• Molecular Formula: C₁₅H₁₀N₄
• Molecular Weight: 246.2667
• Mol File: 70591-70-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine(70591-70-7)
• EPA Substance Registry System: 3-phenyl-[1,2,4]triazolo[3,4-a]phthalazine(70591-70-7)

Safety Data

• Hazardous Substances Data: 70591-70-7(Hazardous Substances Data)

Upstream product

• 1044569-46-1 1-hydrazinophthalazine 
• 98-88-4 benzoyl chloride 
• 67073-46-5 benzaldehyde (1-phthalazine)hydrazone 
• 94445-82-6 1,2-[phenylenebis(methanylidene)] di(benzohydrazide) 
• 112382-00-0 Benzoic acid N'-phthalazin-1-yl-hydrazide; hydrochloride 
• 67073-46-5 benzaldehyde 1-phthalazinylhydrazone 
• 100-52-7 benzaldehyde 
• 643-79-8 o-phthalic dicarboxaldehyde 
• 304-20-1 hydralazine hydrochloride 

Downstream Products

• 130407-96-4 2-(5-Phenyl-2H-[1,2,4]triazol-3-yl)-benzonitrile 
• 104615-52-3 2-(5-Phenyl-2H-[1,2,4]triazol-3-yl)-benzamide 
• 104615-52-3 3-(2-carbamoylphenyl)-5-phenyl-1H-1,2,4-triazole 

Relevant articles and documents

Potential antibacterial agents: Part VI- synthesis and structure elucidation of Schiff bases derived from hydralazine

Synthesis of hydrazones (Schiff bases) of an antihypertensive drug, hydralazine was carried out. The study afforded the hitherto unreported l-[4-chlorobenzylidene]-hydrazinophthalazine (III-a), l-[benzylidene]- hydrazinophthalazine (III-b), l-[4-nitrobenzylidene]-hydrazinophthalazine (III-c), l-[2-nitrobenzylidene]-hydrazinophthalazine (III-d), 3-[4-chlorophenyl]-s-triazolo [3-4-a] phthalazine (IV-a) and 3-phenyl-s-triazolo [3-4-a] phthalazine (IV-b). The structures of these compounds were established using spectroscopic techniques i.e. IR, UV, 1HNMR, EIMS, FD and HRMS. Antibacterial activity of the drugs was evaluated.

Hypervalent iodine mediated synthesis of 3-substituted-s-triazolo phthalazines

Phthalazine hydrazones 1a-g on oxidation with iodobenene diacetate (IBD) in dichloromethane yield exclusively the 3-substituted-s-triazolophthalazines 2a-g.

Sysnthesis and spectra of some triazolo and triazinophthalazines of possible hypotensive activity

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