70603-14-4

Basic information

• Product Name: Benzene, 1-(1,2-diphenylethenyl)-4-methyl-
• CAS NO: 70603-14-4
• Molecular Formula: C21H18
• Molecular Weight: 270.374
• Mol File: 70603-14-4.mol
• Article Data: 32

Chemical Properties

• CAS DataBase Reference: Benzene, 1-(1,2-diphenylethenyl)-4-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-(1,2-diphenylethenyl)-4-methyl-(70603-14-4)
• EPA Substance Registry System: Benzene, 1-(1,2-diphenylethenyl)-4-methyl-(70603-14-4)

Safety Data

• Hazardous Substances Data: 70603-14-4(Hazardous Substances Data)

Upstream product

• 3287-02-3 4-(phenylethynyl)toluene 
• 143-66-8 sodium tetraphenyl borate 
• 624-31-7 4-tolyl iodide 
• 536-74-3 phenylacetylene 
• 100-42-5 styrene 
• 67533-31-7 2,2′-(2-phenylethene-1,1-diyl)bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolane) 
• 106-38-7 para-bromotoluene 
• 1391743-16-0 (E)-1-(4',4',5',5'-tetramethyl-1’,3’,2’-dioxaborolan-2’-yl)-1,2-diphenylethene 
• 591-50-4 iodobenzene 
• 766-97-2 4-n-methylphenylacetylene 
• 108-86-1 bromobenzene 
• 645-49-8 cis-stilben 
• 5720-05-8 4-methylphenylboronic acid 
• 91574-95-7 trimethyl((Z)-1,2-diphenylvinyl)stannane 

Downstream Products

• 67879-22-5 1-(4-methylphenyl)-1,2-diphenylethane 
• 104917-36-4 (E,Z)-1,2-diphenyl-2-tolylvinyl bromide 

Relevant articles and documents

One-pot Sonogashira–Hydroarylation reaction catalyzed by anionic palladium complexes in an aqueous medium

It was found that anionic Pd(II) complexes of type [CA]2[PdCl4] and [CA]2[Pd2Cl6] (CA = imidazolium or pyridinium cation) are effective catalysts for copper-free Sonogashira coupling in an aqueous med

Nickel-Catalyzed Hydroarylation of Alkynes under Reductive Conditions with Aryl Bromides and Water

An operationally simple nickel-catalyzed hydroarylation reaction for alkynes is described. This three-component coupling reaction utilizes commercially available alkynes and aryl bromides, along with water and Zn. An air-stable and easily synthesized Ni(II) precatalyst is the only entity used in the reaction that is not commercially available. This reductive cross-coupling reaction displays a fairly unusual anti selectivity when aryl bromides with ortho substituents are used. In addition to optimization data and a preliminary substrate scope, complementary experiments including deuterium labeling studies are used to provide a tentative catalytic mechanism. We believe this report should inspire and inform other Ni-catalyzed carbofunctionalization reactions.

Geometry-Constrained Iminopyridyl Palladium-Catalyzed Hydroarylation of Alkynes to Prepare Tri-substituted Alkenes Using Alcohol as Reductant

We developed an efficient and straightforward method to prepare tri-substituted alkenes through palladium-catalyzed hydroarylation of alkynes with aryl bromides. Diarylacetylenes and alkyl(aryl)acetylenes could be well hydroarylated with various aryl bromides in moderate to excellent yields. Mechanistic studies suggested that alcohol was the reductant to provide hydride through β-H elimination. Gram scale reaction further demonstrated the practicality and efficiency of the newly developed strategy. (Figure presented.).