70607-84-0

Basic information

• Product Name: 2-PYRROLIDINONE-3,3,4,4,5,5-D6
• Synonyms: 2-PYRROLIDINONE-3,3,4,4,5,5-D6;2-Pyrrolidinone--d6;2-Pyrrolidinone-3,3,4,4,5,5-d6
• CAS NO: 70607-84-0
• Molecular Formula: C₄H₇NO
• Molecular Weight: 91.14
• Mol File: 70607-84-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-PYRROLIDINONE-3,3,4,4,5,5-D6(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PYRROLIDINONE-3,3,4,4,5,5-D6(70607-84-0)
• EPA Substance Registry System: 2-PYRROLIDINONE-3,3,4,4,5,5-D6(70607-84-0)

Safety Data

• Hazardous Substances Data: 70607-84-0(Hazardous Substances Data)

Usage

Uses

2-Pyrrolidinone-3,3,4,4,5,5-d6 is D6 labelled 2-Pyrrolidinone which is widely used organic polar solvent for various applications. 2-Pyrrolidinone is also an intermediate in the manufacture of polymers.

Relevant articles and documents

Detection of the in vivo conversion of 2-pyrrolidinone to γ-aminobutyric acid in mouse brain

Labeled γ-aminobutyric acid was detected in mouse brain following intravenous injections of deuterium labeled 2-pyrrolidinone. [2H6]Pyrrolidinone was prepared by the reduction of [2H4]succinimide with lithium aluminum deuteride. Quantification was accomplished by a gas chromatography mass spectrometry assay method. γ-Aminobutyric acid and internal standard, 5-aminovaleric acid, were converted to volatile derivatives by treatment with N,N-dimethylformamide dimethyl acetal. Quantitative estimates were derived from peak area measurements obtained from monitoring the parent ions of the γ-aminobutyric acid and internal standard derivatives by repetitive scanning during the GC run. The conversion of pyrrolidinone to γ-aminobutyric acid may provide a method for labelling central γ-aminobutyric acid pools.