70629-60-6

Basic information

• Product Name: Isopropylhydrazine dihydrochloride
• Synonyms: isopropylhydrazine hydrochloride 2HCL
• CAS NO: 70629-60-6
• Molecular Formula: C₃H₁₀N₂*2ClH
• Molecular Weight: 147.04678
• Mol File: 70629-60-6.mol
• Article Data: 12

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Isopropylhydrazine dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Isopropylhydrazine dihydrochloride(70629-60-6)
• EPA Substance Registry System: Isopropylhydrazine dihydrochloride(70629-60-6)

Safety Data

• Hazardous Substances Data: 70629-60-6(Hazardous Substances Data)

Upstream product

• 175233-53-1 1-isopropylhydrazinecarboxylic acid tert-butyl ester 
• 16689-35-3 tert-butyl 2-(isopropyl)hydrazinecarboxylate 
• 1133463-25-8 1-(isopropyl)-2-tert-butoxycarbonylhydrazine acetate 
• 16689-34-2 tert-butyl isopropylidenecarbazate 
• 1068-55-9 isopropylmagnesium chloride 

Downstream Products

• 93737-04-3 Z-Leu-HN-NH-CH(CH₃)2 
• 92432-33-2 Z-Ala-HN-NH-CH(CH₃)2 
• 92432-52-5 Z-Ser-HN-NH-CH(CH₃)2 
• 133004-68-9 Z-Glu(NH₂)-HN-NH-CH(CH₃)2 
• 92432-52-5 Z-DL-Ser-HN-NH-CH(CH₃)2 
• 60762-49-4 N-[1-(N'-Isopropyl-hydrazinocarbonyl)-3-methylsulfanyl-propyl]-acetamide 
• 92432-44-5 Z-Sar-HN-NH-CH(CH₃)2 
• 97497-96-6 Z-Asp(NH₂)-HN-NH-CH(CH₃)2 
• 97809-29-5 Z-DL-Glu(NH₂)-HN-NH-CH(CH₃)2 
• 94913-19-6 Z-DL-β-Phe-NH-NH-CH(CH3)2 
• 956316-86-2 benzyl 2-(4-((1,3-dioxolan-2-yl)methyl)-5-(4-fluorophenyl)-1-isopropyl-1H-pyrazol-3-yl)ethylcarbamate 
• 1092789-46-2 5-amino-3-(3-ethoxy-4-methoxyphenyl)-1-isopropyl-1H-pyrazole-4-carbonitrile 
• 955103-26-1 C₂₀H₂₃N₃O*ClH 
• 720693-59-4 N-benzyloxy-N-[3-cyclopentyl-(2R)-(N-isopropylhydrazinocarbonyl)-propyl]-formamide 

Relevant articles and documents

Decarboxylative hydrazination of unactivated carboxylic acids by cerium photocatalysis

We report the cerium photocatalyzed radical decarboxylative hydrazination of carboxylic acids with di-tert-butylazodicarboxylate (DBAD). The operationally simple protocol provides rapid access to synthetically useful hydrazine derivatives and overcomes current scope limitations in the photoredox-catalyzed decarboxylation of carboxylic acids.

1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones as PDE1 Inhibitors

The present invention provides 1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-ones and 1,5-dihydro-4H-pyrazolo[4,3-c]pyridin-4-ones of formula (I) as PDE1 inhibitors and their use as a medicament, in particular for the treatment of neurodegenerative disorders and psychiatric disorders.

Reactions of grignard reagents with nitrous oxide

The chemical activation of nitrous oxide (N2O) can be achieved by organocalcium, organosodium, and organolithium compounds. Grignard reagents, on the other hand, are believed to be inert. We demonstrate that this generalization is not correct. Some aliphatic Grignard reagents undergo a rapid conversion when subjected to an atmosphere of N2O. Hydrazones are the main reaction products.