70639-82-6

Basic information

• Product Name: 6-(2-BROMO-ACETYL)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE
• Synonyms: 6-(BROMOACETYL)-2-OXO-1,2,3,4-TETRAHYDROQUINOLINE;6-2-Bromoacetyl-3,4-dihydro-1H-1uinoline-2-one;2(1H)-Quinolinone, 6-(2-bromoacetyl)-3,4-dihydro-;2(1H)-Quinolinone, 6-(2-b...;6-(2-bromoacetyl)-3,4-dihydroquinolin-2(1H)-one;6-(2-Bromoacetyl)-3,4-dihydro-2(1H)-quinolinone;6-(2-BROMO-ACETYL)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE;6-(2-BROMOACETYL)-3,4-DIHYDRO-1H-QUINOLINE-2-ONE
• CAS NO: 70639-82-6
• Molecular Formula: C11H10BrNO2
• Molecular Weight: 268.11
• Mol File: 70639-82-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 469.6 °C at 760 mmHg
• Flash Point: 237.8 °C
• Appearance: /
• Density: 1.545 g/cm³
• Vapor Pressure: 5.42E-09mmHg at 25°C
• Refractive Index: 1.603
• Storage Temp.: 2-8°C
• PKA: 14.04±0.20(Predicted)
• CAS DataBase Reference: 6-(2-BROMO-ACETYL)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(2-BROMO-ACETYL)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE(70639-82-6)
• EPA Substance Registry System: 6-(2-BROMO-ACETYL)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE(70639-82-6)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 70639-82-6(Hazardous Substances Data)

Usage

General Description

6-(2-Bromo-acetyl)-3,4-dihydro-1H-quinolin-2-one is a synthetic chemical compound belonging to the family of quinolinones, specifically a dihydroquinolinone. The bromine atom in its structure signifies that it is a bromoorganic compound. 6-(2-BROMO-ACETYL)-3,4-DIHYDRO-1H-QUINOLIN-2-ONE has potential applications in the field of medicinal chemistry. Its complex molecular structure, consisting of a bromoacetyl group attached to a quinolinone core, makes it valuable for various synthetic transformations. Detailed properties such as the boiling point, melting point, and toxicity are not widely reported and may vary contingent on purity and specific conditions.

InChI:InChI=1/C11H10BrNO2/c12-6-10(14)8-1-3-9-7(5-8)2-4-11(15)13-9/h1,3,5H,2,4,6H2,(H,13,15)

Upstream product

• 553-03-7 3,4-dihydro-2(1H)-quinolone 
• 598-21-0 2-Bromoacetyl bromide 

Relevant articles and documents

Cyclic keto-pyridone-linked heteroaromatic ring compound as well as preparation method and application thereof

The invention belongs to the field of medicinal chemistry, specifically, the invention relates to a cyclic ketone and pyridone hetero-aromatic ring compound as well as a preparation method and an application of the cyclic ketone and pyridone hetero-aromatic ring compound. The structure of the compound is shown as a general formula (I). The compounds or the stereoisomers, racemes, geometric isomers, tautomers, prodrugs, hydrates, solvates or pharmaceutically acceptable salts and pharmaceutical compositions thereof can be used for treating or/and preventing related diseases mediated by the FXIa (Factor XIa for short).