70671-54-4

Basic information

• Product Name: Z-D-LYS-OH
• Synonyms: CBZ-D-LYSINE;Z-D-LYSINE;Z-D-LYS-OH;N-BENZYLOXYCARBONYL-D-LYSINE;N-ALPHA-Z-D-LYSINE;N-ALPHA-CBZ-D-LYSINE;N-ALPHA-BENZYLOXYCARBONYL-D-LYSINE;N-ALPHA-CARBOBENZOXY-D-LYSINE
• CAS NO: 70671-54-4
• Molecular Formula: C₁₄H₂₀N₂O₄
• Molecular Weight: 280.32
• Product Categories: Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids
• Mol File: 70671-54-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 218 °C
• Boiling Point: 497 °C at 760 mmHg
• Flash Point: 254.4 °C
• Appearance: White/Crystalline
• Density: 1.206 g/cm³
• Vapor Pressure: 1.07E-10mmHg at 25°C
• Refractive Index: 1.55
• Storage Temp.: Store at RT.
• PKA: 3.90±0.21(Predicted)
• BRN: 5290234
• CAS DataBase Reference: Z-D-LYS-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-D-LYS-OH(70671-54-4)
• EPA Substance Registry System: Z-D-LYS-OH(70671-54-4)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 70671-54-4(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline

InChI:InChI=1/C14H20N2O4/c15-9-5-4-8-12(13(17)18)16-14(19)20-10-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10,15H2,(H,16,19)(H,17,18)/t12-/m1/s1

Upstream product

• 87797-02-2 benzyloxycarbonyl-lysine 
• 501-53-1 benzyl chloroformate 
• 7274-88-6 D-lysine hydrochloride 

Downstream Products

• 110473-15-9 N-(benzyloxycarbonyl)-D-lysyl-N'-(tert-butyloxycarbonyl)-D-glutamic acid methyl ester 
• 66845-42-9 N^α-(benzyloxycarbonyl)-N^ε-(tert-butoxycarbonyl)-D-lysine 
• 612844-01-6 (R)-6-Azido-2-benzyloxycarbonylamino-hexanoic acid 
• 68223-08-5 (R)-6-acetylamino-2-benzyloxycarbonylaminohexanoic acid 
• 188625-18-5 (R)-6-Amino-2-benzyloxycarbonylamino-hexanoic acid methyl ester 
• 284469-94-9 C₁₈H₂₆N₂O₅ 
• 937244-45-6 methyl (2R)-2-(benzyloxycarbonylamino)-6-(N-(phenylcarbonyloxy)formamido)hexanoate 
• 937244-46-7 methyl (2R)-2-(benzyloxycarbonylamino)-6-(N-(benzyloxy)formamido)hexanoate 
• 937244-48-9 (R)-methyl 6-(N-(benzyloxy)formamido)-2-(2-(2-hydroxyphenyl)-5-methyloxazole-4-carboxamido)hexanoate 
• 937244-44-5 methyl (2R)-2-(benzyloxycarbonylamino)-6-(phenylcarbonyloxyamino)hexanoate 
• 790302-28-2 (2R,3R)-3-Benzyloxycarbonylamino-2-methyl-7-(2-trimethylsilanyl-ethoxymethoxy)-heptanoic acid methyl ester 

Relevant articles and documents

Stereocontrolled synthesis of onchidins

(Chemical Equation Presented) The first total synthesis of a molecule possessing the stereochemistry proposed for onchidin is described. The structure synthesized appears to be different from that of the marine natural product.

Fairly marked enantioselectivity for the hydrolysis of amino acid esters by chemically modified enzymes

The hydrolysis (deacylation) of enantiomeric substrates by the chemically modified enzymes decanoyl-α-chymotrypsin and decanoyl-trypsin was studied. Reaction activity for decanoyl-α-chymotrypsin was lower than that for the native enzyme, although intriguingly the enantioselectivity was markedly enhanced as compared with the native enzyme. In particular, the apparently complete enantioselective catalysis was attained for the hydrolytic cleavage of p-nitrophenyl N-dodecanoyl- D(L)-phenylalaninates. The enhancement of enantioselectivity, however, was not observed for decanoyl-trypsin. These results suggest that the chemically modified α-chymotrypsin by addition of hydrophobic groups has promoted enantioselectivity for the hydrolysis of hydrophobic esters.