70711-53-4 Usage
Description
Phenindione-D5 is a deuterated analog of the antiplatelet drug Phenindione, characterized by the presence of five deuterium atoms. It is commonly used as an internal standard in analytical chemistry for the quantification of Phenindione and related compounds. Due to its stable isotopic composition, Phenindione-D5 provides enhanced sensitivity and accuracy in mass spectrometry-based assays.
Uses
Used in Pharmaceutical Industry:
Phenindione-D5 is used as a proton pump inhibitor and traditional nonsteroidal anti-inflammatory drug for the treatment of acute interstitial nephritis and acute kidney injury. Its deuterated nature allows for improved pharmacokinetic properties and reduced potential for drug-drug interactions.
Used in Analytical Chemistry:
Phenindione-D5 is used as an internal standard for the quantification of Phenindione and related compounds in various biological samples. Its stable isotopic composition provides enhanced sensitivity and accuracy in mass spectrometry-based assays, ensuring reliable and precise measurements.
Used in Research and Development:
Phenindione-D5 serves as a valuable tool in the development of new drugs and therapies targeting platelet aggregation and inflammation. Its use in preclinical studies and pharmacological research helps to elucidate the mechanisms of action and potential side effects of Phenindione and its analogs.
Check Digit Verification of cas no
The CAS Registry Mumber 70711-53-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,7,1 and 1 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 70711-53:
(7*7)+(6*0)+(5*7)+(4*1)+(3*1)+(2*5)+(1*3)=104
104 % 10 = 4
So 70711-53-4 is a valid CAS Registry Number.
70711-53-4Relevant articles and documents
Ru(II)-Catalyzed C-H Activation and Alkyne Annulation Reaction of Phenyl Indandiones: Synthesis of Spirobi[indene]diones
Bora, Bidisha R.,Sultana, Sabera,Sarma, Bipul,Gogoi, Sanjib
, p. 2907 - 2915 (2022/04/25)
A Ru(II)-catalyzed synthesis of spirobi[indene]dione from phenyl indandione and alkyne is reported. This metal-catalyzed cyclization reaction proceeds through hydroxy group directed C(sp2)-H bond activation, keto-enol tautomerization and alkyne annulation pathways.
