70769-85-6

Basic information

• Product Name: (R)-2-((R)-Hydroxy-phenyl-methyl)-but-3-enoic acid tert-butyl ester
• CAS NO: 70769-85-6
• Molecular Weight: 248.322
• Mol File: 70769-85-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2-((R)-Hydroxy-phenyl-methyl)-but-3-enoic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-((R)-Hydroxy-phenyl-methyl)-but-3-enoic acid tert-butyl ester(70769-85-6)
• EPA Substance Registry System: (R)-2-((R)-Hydroxy-phenyl-methyl)-but-3-enoic acid tert-butyl ester(70769-85-6)

Safety Data

• Hazardous Substances Data: 70769-85-6(Hazardous Substances Data)

Upstream product

• 14036-55-6 t-butyl vinylacetate 
• 79218-15-8 tert-butyl (E)-crotonate 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Total regio- and diastereocontrol in the aldol reactions of dienolborinates

It is reported that appropriate dienolborinates can provide access to both diastereomers of 2-(hydroxymethyl)but-3-enoates through exclusive α-regiocontrol in a non-vinylogous pathway. Contrary to previous reports in which dialkylchloroboranes failed to enolize propanoates, acidity-enhanced but-3-enoates readily undergo enolization, offering unprecedented control over the formation of these valuable synthons. The first example of an aldol reaction in the presence of a phosphine-borane adduct is also reported.