70780-36-8

Basic information

• Product Name: 1H-Indene-1,3(2H)-dione, 2-hydroxy-2-(2-oxo-2-phenylethyl)-
• CAS NO: 70780-36-8
• Molecular Formula: C17H12O4
• Molecular Weight: 280.28
• Mol File: 70780-36-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Indene-1,3(2H)-dione, 2-hydroxy-2-(2-oxo-2-phenylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indene-1,3(2H)-dione, 2-hydroxy-2-(2-oxo-2-phenylethyl)-(70780-36-8)
• EPA Substance Registry System: 1H-Indene-1,3(2H)-dione, 2-hydroxy-2-(2-oxo-2-phenylethyl)-(70780-36-8)

Safety Data

• Hazardous Substances Data: 70780-36-8(Hazardous Substances Data)

Upstream product

• 485-47-2 indan-1,2,3-trione hydrate 
• 98-86-2 acetophenone 

Downstream Products

• 128404-65-9 13-benzoylindeno<1',2':5,4>pyrrolo<2,1-a>phthalazin-12-one 
• 1431986-45-6 2-(6,6-dimethyl-4-oxo-2-phenyl-1-(p-tolyl)-4,5,6,7-tetrahydro-1H-indol-3-yl)-1H-indene-1,3(2H)-dione 
• 1431986-46-7 2-(1-(4-chlorophenyl)-6,6-dimethyl-4-oxo-2-phenyl-4,5,6,7-tetrahydro-1H-indol-3-yl)-1H-indene-1,3(2H)-dione 
• 77152-22-8 NSC 663883 
• 128404-61-5 13-benzoylindeno<2,1-b>benzoindolizin-12-one 

Relevant articles and documents

Chemistry of Free Cyclic Vicinal Tricarbonyl Compounds ('1,2,3-Triones'). Part 3. Polar and Redox Reactions of 1,2,3-Triones with Enamines of Different Types - News on Oxonol Dyes, Radicals, and Biradicals

The central C=O groups of cyclic 1,2,3-triones possess outstanding electrophilic (electron-pair-accepting) as well as oxidizing (one-electron-accepting) properties. Thus, 1,2,3-triones are chemically related to 1,2- and 1,4-benzoquinones. Whereas polar reactions with carbanion-like (electron rich) species give rise to nucleophilic addition reactions to C=O groups under exclusive C,C-bond formation, SET (single-electron transfer) or redox reactions effect a partial 'carbonyl Umpolung' via ketyl intermediates (C,C- and/or C,O-bond formation). Here, we report on numerous reactions between electron-rich, more- or less-polar enamines with 5,5-dimethylcyclohexane-1,2,3-trione (9a) and 1H-indene-1,2,3-trione (9b). Various new derivatives of basic oxonol dyes were formed, including the first oxonol dye incorporating a 1,3-dioxocyclohexyl moiety. A novel stable radical, 50/50′, was obtained from 9b and lla via addition, hydrolysis, and treatment with conc. H2SO4. Radical 50/50′ represents a vinylogous 'monodehydroreductone' and is, thus, related to monodehydroascorbic acid (143), to Russell's radical cation (144), to indigo (141/141′), and to quinhydrone.

"ONE-STEP" SYNTHESIS OF AN INDENO-INDOLILZINE NUCLEUS

The reaction of 2-hydroxy-2-phenacyl-1,3-indanedione with tosyl chloride in pyridine directly afforded in high yield the 11-benzoyl-10H-indenoindolizine-10-one the structure of which has been determined by single crystal X-ray diffraction.A possibl