70787-27-8

Basic information

• Product Name: N-(2-bromophenyl)benzamide
• Synonyms: N-(2-bromophenyl)benzamide;NSC 406273;2-Bromo-N-benzoylaniline
• CAS NO: 70787-27-8
• Molecular Formula: C₁₃H₁₀BrNO
• Molecular Weight: 276.1286
• Mol File: 70787-27-8.mol
• Article Data: 48

Chemical Properties

• Boiling Point: 291°Cat760mmHg
• Flash Point: 129.8°C
• Appearance: /
• Density: 1.496g/cm³
• Vapor Pressure: 0.002mmHg at 25°C
• Refractive Index: 1.665
• CAS DataBase Reference: N-(2-bromophenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromophenyl)benzamide(70787-27-8)
• EPA Substance Registry System: N-(2-bromophenyl)benzamide(70787-27-8)

Safety Data

• Hazardous Substances Data: 70787-27-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C13H10BrNO/c14-11-8-4-5-9-12(11)15-13(16)10-6-2-1-3-7-10/h1-9H,(H,15,16)

Upstream product

• 98-88-4 benzoyl chloride 
• 615-36-1 2-bromoaniline 
• 147542-38-9 N-(2,4-dibromophenyl)benzamide 
• 349613-49-6 4-bromo-N-(2-bromophenyl)benzamide 
• 118-92-3 anthranilic acid 
• 183209-26-9 ortho-bromophenyl isocyanide 
• 85433-21-2 N-(2-bromophenyl)benzothioamide 
• 591-50-4 iodobenzene 
• 201230-82-2 carbon monoxide 
• 108-86-1 bromobenzene 
• 93-89-0 benzoic acid ethyl ester 
• 577-19-5 2-nitrophenyl bromide 
• 100-52-7 benzaldehyde 
• 1333236-28-4 C₁₃H₁₀BrNOS 

Downstream Products

• 85433-21-2 N-(2-bromophenyl)benzothioamide 
• 70787-28-9 N-(2-Bromphenyl)benzimidoylchlorid 
• 94191-65-8 N-<2-(1-methylimidazol-2-yl)phenyl>benzamide 
• 122-39-4 diphenylamine 
• 90395-48-5 benzoic acid-(2-[3]pyridyl-anilide) 
• 1015-89-0 6(5H)-phenanthridinone 
• 23564-70-7 N-(o-Hydroxyphenol)benzamidine 
• 119488-08-3 N-allyl benz(o-bromo)anilide 
• 112671-41-7 N-{2-[(trimethylsilanyl)ethynyl]phenyl}benzamide 
• 135308-46-2 C₂₀H₁₇NO₂ 
• 584-70-3 N-benzoyl-2-methylaniline 
• 213327-30-1 N-benzoyl-N-(2-bromo-phenyl)-benzamide 
• 223520-89-6 2-benzamidobenzenephosphonic acid diethyl ester 
• 833-50-1 2-phenylbenzo[d]oxazole 

Relevant articles and documents

Pd-Catalyzed Carbonylative Synthesis of 4H-Benzo[d][1,3]Oxazin-4-Ones Using Benzene-1,3,5-Triyl Triformate as the CO Source

A facile synthesis of 4H-benzo[d][1,3]oxazin-4-one derivatives by Pd-catalyzed carbonylative cross-coupling between N-(ortho-bromoaryl)amides and benzene-1,3,5-triyl triformate (TFBen) was developed. This procedure does not require the toxic and flammable gas CO as the carbonyl source and tolerates a wide scope of functional groups. Remarkably, 4H-benzo[d][1,3]oxazin-4-ones incorporated to natural products and drugs can be constructed by this method.

Photocatalyst- And Transition-Metal-Free Visible-Light-Promoted Intramolecular C(sp2)-S Formation

A photocatalyst- and transition-metal-free visible-light-induced cyclization of ortho-halothiobenzanilides has been developed. Upon irradiation with visible light, substrates undergo dehalogenative cyclization to 2-aryl benzothiazoles with high efficiency and selectivity. This photocyclization exhibits a high tolerance to various functional groups, is applicable for the synthesis of 2-alkyl benzothiazoles, and is easy to set up for gram-scale reaction.

Practical bromination of arylhydroxylamines with SOBr2 towards ortho-bromo-anilides

A facile approach for synthesizing ortho-bromoanilides from readily available aryhydroxylamines and thionyl bromide is demonstrated in this work. Mild reaction conditions and broad scope of substrates ranging from heterocyclic structures to pharmaceutics-potential motifs are used in the reactions of this paper. Efficient bromination of ortho C–H bonds of the aryhydroxylamines has been achieved. Ortho-bromoanilide products were obtained in good to excellent yields, and model scaled-up reactions of this synthetic approach are shown in this work.