70841-77-9Relevant articles and documents
Enantioselective decarboxylation-reprotonation of an α-amino malonate derivative as a route to optically enriched cyclic α-amino acid
Rogers, Louis M.-A.,Rouden, Jacques,Lecomte, Ludovic,Lasne, Marie-Claire
, p. 3047 - 3050 (2003)
Chiral tertiary amines have been examined as enantioselective decarboxylation-reprotonation reagents for the synthesis of α-amino acids via α-aminomalonates. N-Acetyl pipecolic acid ethyl ester, as a model compound, was obtained in good yield and 52% enantiomeric excess using a quinidine derived base.