7091-05-6

Basic information

• Product Name: 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione
• Synonyms: 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione;9β,11β-EPOXY-17-21-DIHYDROXYPREGNA-1,4-DIENE-3,20-DIONE;(4aS,4bS,5aS,6aS,7R,9aS,9bS)-7-hydroxy-7-(2-hydroxyacetyl)-4a,6a-dimethyl-5a,6,6a,7,8,9,9a,9b,10,11-decahydrocyclopenta[1,2]phenanthro[4,4a-b]oxiren-2(4aH)-one
• CAS NO: 7091-05-6
• Molecular Formula: C₂₁H₂₆O₅
• Molecular Weight: 358.43
• EINECS: 230-394-1
• Mol File: 7091-05-6.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 564.24 °C at 760 mmHg
• Flash Point: 200.953 °C
• Appearance: /
• Density: 1.355 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.627
• PKA: 12.54±0.60(Predicted)
• CAS DataBase Reference: 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione(7091-05-6)
• EPA Substance Registry System: 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione(7091-05-6)

Safety Data

• Hazardous Substances Data: 7091-05-6(Hazardous Substances Data)

Usage

Description

9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione is a steroid compound with a unique chemical structure characterized by the presence of an epoxy group at the 9,11 positions, and hydroxyl groups at the 17 and 21 positions. It belongs to the class of pregnane steroids and exhibits significant pharmaceutical interest due to its potential therapeutic properties.

Uses

Used in Pharmaceutical Industry:
9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione is used as a pharmaceutical compound for its potential therapeutic applications. The steroidal structure of this molecule allows it to interact with various biological targets, making it a promising candidate for the development of drugs targeting hormonal imbalances, inflammation, and other conditions related to the endocrine system.
Used in Steroid Research:
In addition to its direct pharmaceutical applications, 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione is also used as a starting material or intermediate in the synthesis of other steroidal compounds with potential medicinal properties. Its unique structural features make it a valuable tool for researchers in the field of steroid chemistry and drug development.
Used in Hormone Regulation:
Due to its structural similarity to natural hormones, 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione may be used as a hormone regulator or modulator. It could potentially be employed in the treatment of conditions related to hormonal imbalances, such as adrenal disorders, menstrual disorders, or certain types of cancer that are hormone-responsive.
Used in Anti-Inflammatory Applications:
The steroidal nature of 9b,11b-Epoxy-17,21-dihydroxypregna-1,4-diene-3,20-dione may also make it useful in the development of anti-inflammatory drugs. Steroids are known for their ability to modulate the immune system and reduce inflammation, making this compound a potential candidate for the treatment of conditions such as arthritis, autoimmune diseases, and other inflammatory disorders.

InChI:InChI=1/C21H26O5/c1-18-7-5-13(23)9-12(18)3-4-15-14-6-8-20(25,16(24)11-22)19(14,2)10-17-21(15,18)26-17/h5,7,9,14-15,17,22,25H,3-4,6,8,10-11H2,1-2H3/t14-,15-,17-,18-,19-,20-,21+/m0/s1