70931-59-8

Basic information

• Product Name: 1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE
• Synonyms: 1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE;1-(Bromomethyl)-4-fluoro-2-iodobenzene, alpha-Bromo-4-fluoro-2-iodotoluene;4-Fluoro-2-iodobenzyl bromide
• CAS NO: 70931-59-8
• Molecular Formula: C₇H₅BrFI
• Molecular Weight: 314.9214732
• Mol File: 70931-59-8.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 277.5±25.0 °C(Predicted)
• Appearance: /
• Density: 2.168±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE(70931-59-8)
• EPA Substance Registry System: 1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE(70931-59-8)

Safety Data

• Hazardous Substances Data: 70931-59-8(Hazardous Substances Data)

Usage

General Description

1-Bromomethyl-4-fluoro-2-iodo-benzene is a chemical compound with the molecular formula C7H5BrFI. It is a halogenated aromatic compound that contains a bromomethyl group, a fluoro group, and an iodo group attached to a benzene ring. 1-BROMOMETHYL-4-FLUORO-2-IODO-BENZENE is often used as a building block in organic synthesis, particularly in the creation of pharmaceuticals and agrochemicals. Its unique structure and functional groups make it a valuable starting material for the development of new chemical compounds with potential biological or industrial applications. However, it is important to handle this chemical with care and use appropriate safety measures, as it can be hazardous if not handled properly.

Upstream product

• 13194-67-7 4-fluoro-2-iodotoluene 
• 446-10-6 2-nitro-4-fluorotoluene 
• 367-29-3 3-fluoro-6-methylaniline 
• 56096-89-0 4-fluoro-2-iodobenzoic acid 

Downstream Products

• 70931-60-1 (4-fluoro-2-iodophenyl)acetonitrile 
• 606138-71-0 C₁₇H₂₃FINO₄ 
• 569354-60-5 N-methyl 2-aminomethyl-5-fluorobenzenecarboxamide HCl salt 
• 606080-42-6 5-(1,1-dioxido-1,2-thiazinan-2-yl)-N-{4-fluoro-2-[(methylamino)carbonyl]benzyl}-8-hydroxy-1,6-naphthyridine-7-carboxamide 
• 70931-61-2 (4-fluoro-2-iodophenyl)acetic acid 
• 73128-99-1 (4-Fluoro-2-phenylsulfanyl-phenyl)-acetic acid 
• 606080-38-0 1-(azidomethyl)-4-fluoro-2-iodobenzene 
• 1401971-06-9 4-fluoro-2-iodo-1-(methoxymethyl)benzene 
• 1188513-89-4 1-chloromethyl-4-fluoro-2-iodo-benzene 
• 1394351-48-4 C₁₉H₁₅F₂I₂NO₂ 
• 1394350-91-4 1,3-bis(4-fluoro-2-iodophenyl)propan-2-amine 
• 1394351-09-7 (S)-ethyl 2-(4-fluoro-2-iodobenzyl)-6-fluoroindoline-2-carboxylate 
• 1394351-20-2 (S)-2-(4-fluoro-2-iodobenzyl)-6-fluoroindoline 
• 1394350-78-7 ethyl 2-(4-fluoro-2-iodobenzyl)-2-amino-3-(4-fluoro-2-iodophenyl)propanoate 

Relevant articles and documents

Access to chiral tetrahydrofluorenes through a palladium-catalyzed enantioselective tandem intramolecular Heck/Tsuji-Trost reaction

A palladium-catalyzed enantioselective coupling of 2,5-cyclohexadienyl-substituted aryl iodides and carbon or heteroatom nucleophiles is described. The reaction proceeded via a tandem asymmetric Heck insertion and Tsuji-Trost allylation, enabling the rapi

A concise synthesis of chiral indanes as α1A adrenoceptor partial agonists

The synthesis of a series of chiral indanes with reported α1A partial agonist activity is outlined, applying a rhodium catalysed cyclisation for template construction. This method was extended to the asymmetric synthesis of lead compound PF-037

Novel 2-imidazoles as potent, selective and CNS penetrant α1A adrenoceptor partial agonists

A novel series of central nervous system (CNS) penetrant indane 2-imidazoles have been identified as potent, partial agonists of the α1A adrenergic receptor, having good selectivity over the α1B, α1D and α2 sub-